BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS

Title:

BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS

Document Type and Number:

WIPO Patent Application WO1999026932

Kind Code:

A8

Abstract:

The present invention relates to novel biheterocyclic derivatives which are factor Xa inhibitors; the pharmaceutically acceptable salts and N-oxides thereof; their uses as therapeutic agents and the methods of their making.

Inventors:

FATHEREE PAUL R
JENKINS THOMAS E
LI YONG
LINSELL MARTIN S
RAI ROOPA
SHRADER WILLIAM D
TRAPP SEAN G
YOUNG WENDY B

Application Number:

PCT/US1998/025216

Publication Date:

September 10, 1999

Filing Date:

November 25, 1998

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Assignee:

AXYS PHARM INC (US)

International Classes:

C07D235/20; C07D403/14; C07D405/14; C07D413/14; C07D417/06; C07D453/02; C07D521/00; (IPC1-7): C07D235/20; A61K31/415; C07D403/14; C07D405/14; C07D413/14; C07D417/06; C07D453/02

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