C-LINKED CYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS

Title:

C-LINKED CYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS

Document Type and Number:

WIPO Patent Application WO2007002635

Kind Code:

B1

Abstract:

The present invention provides novel C-linked cyclic compounds and analogues of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein. These compounds are selective inhibitors of the human P2Y₁ receptor which can be used as medicaments.

Inventors:

THIBEAULT CARL (CA)
SUTTON JAMES C (US)
QIAO JENNIFER X (US)
RUEL REJEAN (CA)

Application Number:

PCT/US2006/024911

Publication Date:

May 18, 2007

Filing Date:

June 26, 2006

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Assignee:

BRISTOL MYERS SQUIBB CO (US)
THIBEAULT CARL (CA)
SUTTON JAMES C (US)
QIAO JENNIFER X (US)
RUEL REJEAN (CA)

International Classes:

C07D209/14; C07C275/28; C07C275/30; C07D209/08; C07D213/61; C07D213/64; C07D213/75; C07D215/12; C07D235/18; C07D307/87; C07D317/58; C07D333/58; C07D401/04; C07D405/04; C07D409/04

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