Title:
COMPOSITION FOR ACTIVATING Toll-LIKE RECEPTOR 2
Document Type and Number:
WIPO Patent Application WO/2018/190407
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a novel composition for activating a Toll-like receptor 2. The present invention provides a composition for activating a Toll-like receptor 2 (TLR2) that includes bacteria belonging to Bifidobacterium bifidum or a treated product thereof as an active ingredient.
Inventors:
JINNO SHINJI (JP)
NAKAMURA YOSHITAKA (JP)
YAMAZAKI KAE (JP)
NAKAMURA YOSHITAKA (JP)
YAMAZAKI KAE (JP)
Application Number:
PCT/JP2018/015465
Publication Date:
October 18, 2018
Filing Date:
April 13, 2018
Export Citation:
Assignee:
MEIJI CO LTD (JP)
International Classes:
A61K35/745; A23L33/135; A61P1/04; A61P1/12; A61P37/08; A61P43/00; C12N1/20
Domestic Patent References:
| WO2006087913A1 | 2006-08-24 |
Foreign References:
| JP2014505065A | 2014-02-27 |
Other References:
KHAILOVA, L. ET AL.: "Bifidobacterium bifidum reduces apoptosis in the intestinal epithelium in necrotizing enterocolitis", AM J PHYSIOL GASTROINTEST LIVER PHYSIOL, vol. 299, November 2010 (2010-11-01), pages G1118 - G1127, XP055559281, ISSN: 0193-1857, Retrieved from the Internet
NAKAMURA, YOSHITAKA ET AL.: "Bifidobacterium bifidum OLB6378 as a potential for enhanced IgA secretion: its selection and mechanism", CELL, vol. 47, no. 2, 20 February 2015 (2015-02-20), pages 49 - 53, XP009510112, ISSN: 1346-7557
NAKAMURA, YOSHITAKA ET AL.: "Bifidobacterium bifidum OLB6378 as a potential for enhanced IgA secretion: its selection and mechanism", CELL, vol. 47, no. 2, 20 February 2015 (2015-02-20), pages 49 - 53, XP009510112, ISSN: 1346-7557
Attorney, Agent or Firm:
YOKOTA Nobutaka et al. (JP)
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