Title:
CALORIMETRIC MEASURING DEVICE
Document Type and Number:
WIPO Patent Application WO2006110964
Kind Code:
A3
Abstract:
A calorimetric measuring device as subject of the present invention, for qualitative or quantitative analysis of the enthalpy of a buffer and one or more reagents, comprises a first open calorimeter for to receiving a buffer solution and one or more reagents, and a second open calorimeter for receiving a reference buffer solution. The calorimetric measuring device further comprises a means for registration of a signal being function of the temperature difference between the first open calorimeter and the second open calorimeter.
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Inventors:
HOFLACK LIEVE (BE)
VAN GERWEN PETER (BE)
VERHAEGEN KATARINA (BE)
PAPEN ROELAND (US)
VAN GERWEN PETER (BE)
VERHAEGEN KATARINA (BE)
PAPEN ROELAND (US)
Application Number:
PCT/BE2006/000039
Publication Date:
December 28, 2006
Filing Date:
April 21, 2006
Export Citation:
Assignee:
VIVACTIS N V (BE)
HOFLACK LIEVE (BE)
VAN GERWEN PETER (BE)
VERHAEGEN KATARINA (BE)
PAPEN ROELAND (US)
HOFLACK LIEVE (BE)
VAN GERWEN PETER (BE)
VERHAEGEN KATARINA (BE)
PAPEN ROELAND (US)
International Classes:
G01N25/48
Domestic Patent References:
| WO2001085901A2 | 2001-11-15 | |||
| WO2005003765A1 | 2005-01-13 | |||
| WO2000079254A1 | 2000-12-28 |
Foreign References:
| EP1265073A2 | 2002-12-11 |
Other References:
PIERCE M M ET AL: "Isothermal Titration Calorimetry of Protein-Protein Interactions", METHODS : A COMPANION TO METHODS IN ENZYMOLOGY, ACADEMIC PRESS INC., NEW YORK, NY, US, vol. 19, no. 2, October 1999 (1999-10-01), pages 213 - 221, XP004466826, ISSN: 1046-2023
BRANDTS J F ET AL: "AN INSTRUMENT FOR RAPID DETERMINATION OF BINDING CONSTANTS FOR BIOMOLECULES", AMERICAN LABORATORY, INTERNATIONAL SCIENTIFIC COMMUNICATIONS, SHELTON,, US, May 1990 (1990-05-01), pages 30 - 41, XP000974446, ISSN: 0044-7749
SPENCER SHAWN D ET AL: "Isothermal titration calorimetric study of RNase-A kinetics (cCMP fwdarw 3'-CMP) involving end-product inhibition", PHARMACEUTICAL RESEARCH (DORDRECHT), vol. 21, no. 9, September 2004 (2004-09-01), pages 1642 - 1647, XP002401673, ISSN: 0724-8741
BRANDTS J F ET AL: "AN INSTRUMENT FOR RAPID DETERMINATION OF BINDING CONSTANTS FOR BIOMOLECULES", AMERICAN LABORATORY, INTERNATIONAL SCIENTIFIC COMMUNICATIONS, SHELTON,, US, May 1990 (1990-05-01), pages 30 - 41, XP000974446, ISSN: 0044-7749
SPENCER SHAWN D ET AL: "Isothermal titration calorimetric study of RNase-A kinetics (cCMP fwdarw 3'-CMP) involving end-product inhibition", PHARMACEUTICAL RESEARCH (DORDRECHT), vol. 21, no. 9, September 2004 (2004-09-01), pages 1642 - 1647, XP002401673, ISSN: 0724-8741
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