CANCER-LINKED GENE AS TARGET FOR CHEMOTHERAPY

Title:

CANCER-LINKED GENE AS TARGET FOR CHEMOTHERAPY

Document Type and Number:

WIPO Patent Application WO2003075854

Kind Code:

A8

Abstract:

Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosis using the gene sequences.

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Inventors:

YOUNG PAUL E (US)
EBNER REINHARD (US)
STROVEL JEFFREY W (US)

Application Number:

PCT/US2003/007147

Publication Date:

May 18, 2006

Filing Date:

March 07, 2003

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Assignee:

AVALON PHARMACEUTICALS (US)
YOUNG PAUL E (US)
EBNER REINHARD (US)
STROVEL JEFFREY W (US)

International Classes:

C12Q1/68; G01N33/50; G01N33/574; (IPC1-7): C12Q1/68; C07K14/00; C07K16/00; A61K38/00; A61K48/00

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