Title:
CANCER-TREATING AGENT THAT TARGETS AT LONG-CHAIN NON-CODING RNA, AND CANCER DIAGNOSIS METHOD
Document Type and Number:
WIPO Patent Application WO/2019/189772
Kind Code:
A1
Abstract:
In the present description, a cancer-treating agent is provided, which contains at least one component selected from a TM4SF1AS1 expression inhibitor, a PURA expression inhibitor and a YB1 expression inhibitor.
Inventors:
KITAJIMA HIROSHI (JP)
MARUYAMA REO (JP)
YAMAMOTO EIICHIRO (JP)
SUZUKI HIROMU (JP)
MARUYAMA REO (JP)
YAMAMOTO EIICHIRO (JP)
SUZUKI HIROMU (JP)
Application Number:
PCT/JP2019/014028
Publication Date:
October 03, 2019
Filing Date:
March 29, 2019
Export Citation:
Assignee:
UNIV SAPPORO MEDICAL (JP)
International Classes:
A61K45/00; A61K31/7088; A61K31/7105; A61K31/713; A61K35/13; A61K45/06; A61K48/00; A61P1/04; A61P1/16; A61P15/00; A61P35/00; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/113; C12N15/63; C12Q1/68
Foreign References:
| JP2016192963A | 2016-11-17 |
Other References:
DATABASE NCBI [online] 26 June 2017 (2017-06-26), "Homo sapiens TM4SF1 antisense RNA 1 (TM4SF1-AS1), transcript variant 2, long non-coding RNA", Database accession no. NR_046650
INOUE T. ET AL.: "Purine-rich element binding protein (PUR) alpha induces endoplasmic reticulum stress response, and cell differentiation pathways in prostate cancer cells.", PROSTATE, vol. 69, no. 8, 2009, pages 861 - 873
GUO Z.M. ET AL.: "Purine-rich element binding protein alpha promotes invasion and migration of esophageal squamous cell carcinoma KYSE 510 cells by inducing epithelialmesenchymal transition.", WORLD CHIN. J. DIGESTOLOGY, vol. 22, no. 36, 2014, pages 5579 - 5586
INOUE T. ET AL.: "Purine-rich element binding protein (PUR) alpha induces endoplasmic reticulum stress response, and cell differentiation pathways in prostate cancer cells.", PROSTATE, vol. 69, no. 8, 2009, pages 861 - 873
GUO Z.M. ET AL.: "Purine-rich element binding protein alpha promotes invasion and migration of esophageal squamous cell carcinoma KYSE 510 cells by inducing epithelialmesenchymal transition.", WORLD CHIN. J. DIGESTOLOGY, vol. 22, no. 36, 2014, pages 5579 - 5586
Attorney, Agent or Firm:
KUZUWA, Kiyoshi (JP)
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