CARBOHYDRATE CONJUGATES TO PREVENT ABUSE OF CONTROLLED SUBSTANCES

Title:

CARBOHYDRATE CONJUGATES TO PREVENT ABUSE OF CONTROLLED SUBSTANCES

Document Type and Number:

WIPO Patent Application WO2004062614

Kind Code:

A3

Abstract:

The invention provides a "street-safe" version of a controlled substance that permits the therapeutically beneficial effects of the substance while reducing or eliminating the euphoric effects that lead to substance abuse. The invention provides pharmaceutical compositions comprising a controlled substance and a carbohydrate covalently bound to said controlled substance in a manner that renders said controlled substance pharmacologically inactive or substantially diminishes its activity and methods of using the same.

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Inventors:

MICKLE TRAVIS (US)
PICCARIELLO THOMAS (US)
MONCRIEF JAMES SCOTT (US)
BOERTH NANCY JOHNSTON (US)
BISHOP BARNEY (US)

Application Number:

PCT/US2004/000646

Publication Date:

May 06, 2005

Filing Date:

January 13, 2004

Export Citation:

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Assignee:

NEW RIVER PHARMACEUTICALS INC (US)
MICKLE TRAVIS (US)
PICCARIELLO THOMAS (US)
MONCRIEF JAMES SCOTT (US)
BOERTH NANCY JOHNSTON (US)
BISHOP BARNEY (US)

International Classes:

A61K31/485; A61K31/70; A61K45/06; A61K47/48; (IPC1-7): A61K31/70

Foreign References:

US6713452B2	2004-03-30
US20040161382A1	2004-08-19
US20030130205A1	2003-07-10

Other References: