CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF

Title:

CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2023/213310

Kind Code:

A1

Abstract:

A water-soluble carbon chain substance for regulating transmembrane transport and fluidity of cell membranes, and the preparation and use thereof. The water-soluble carbon chain substance comprises a carbon chain which originally has a certain water solubility, and the structure thereof comprises at least one or more hydrophobic carbon chain parts and one or more hydrophilic groups or residues; and also comprises a high-hydrophilicity complex formed by coupling a hydrophobic carbon chain part to a water-soluble molecule; the water-soluble carbon chain can be used for preventing and treating infection including viruses, bacteria and fungi, anti-ageing, and preventing and reducing the occurrence of neurodegenerative diseases such as Alzheimer's disease; by reducing the non-specific phagocytosis of the nano-drug by cells, the effect of the nano-drug on target lesions is improved.

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Inventors:

ZHAO YILIN (CN)
CHEN WEIBIN (CN)
ZHOU YUANYUAN (CN)
LIU FENGWU (CN)
LIU HONGYI (CN)
ZHOU XU (CN)
WAN ZHENG (CN)
MA LIN (CN)

Application Number:

PCT/CN2023/092349

Publication Date:

November 09, 2023

Filing Date:

May 05, 2023

Export Citation:

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Assignee:

SUNFOREST BEIJNG BIOPHARM LTD (CN)

International Classes:

A01P1/00; A61K45/00; A01P3/00; A61K31/20; A61K47/54; A61K47/61; A61K47/64; A61P31/04; A61P31/10; A61P31/12; A61P31/16; A61P31/18; A61P31/20; A61P31/22

Foreign References:

EP3992205A1	2022-05-04
US20170119720A1	2017-05-04
US20130266611A1	2013-10-10
US20210317457A1	2021-10-14
CN115607677A	2023-01-17
CN114569726A	2022-06-03
CN114788872A	2022-07-26

Attorney, Agent or Firm:

GEXU INTELLECTUAL PROPERTY LAW FIRM (CN)

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