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Title:
CARBON-CARBON CROSS COUPLING CATALYZED BY TRANSITION METALS ON SOLID SUPPORTS
Document Type and Number:
WIPO Patent Application WO2005051869
Kind Code:
A3
Abstract:
The present invention provides methods of coupling carbon-containing compounds using a transition metal or transition metal complex on a solid support. The solid support can include alkaline earth metal salts, including carbonate and sulfate salts. The transition metals can include palladium or nickel metal. The method can include combining two carbon containing compounds and a transition metal or transition metal complex on a solid support in the presence of a solvent, desirably an alcohol.

Inventors:
WILK BOGDAN KAZIMIERZ (US)
Application Number:
PCT/US2004/039015
Publication Date:
April 06, 2006
Filing Date:
November 19, 2004
Export Citation:
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Assignee:
WYETH CORP (US)
WILK BOGDAN KAZIMIERZ (US)
International Classes:
B01J21/00; B01J23/00; B01J23/58; B01J31/00; B01J31/02; C07B37/04; C07C1/20; C07C2/68; C07D265/18; B01J23/44; B01J23/62; B01J23/755; B01J23/78; B01J27/053; B01J27/232; B01J31/18; B01J31/24; (IPC1-7): C07D265/18; B01J21/00; B01J23/00
Domestic Patent References:
WO2000066164A12000-11-09
WO1999012940A11999-03-18
Other References:
ZHANG, P.; ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, no. 20, 2002, pages 4379 - 4382, XP002335736
HASSAN J ET AL: "Aryl-Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction", CHEMICAL REVIEWS, AMERICAN CHEMICAL SOCIETY. EASTON, US, vol. 102, no. 5, 8 March 2002 (2002-03-08), pages 1359 - 1469, XP002245414, ISSN: 0009-2665
COURTOIS, V.; ET AL., TETRAHEDRON LETTERS, vol. 40, 1999, pages 5993 - 5996, XP004173908
ANDERSEN, N.G.; ET AL., J. ORG. CHEM., vol. 61, 1996, pages 9556 - 9559, XP002335738
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