Title:
CARBON QUANTUM DOTS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/087646
Kind Code:
A1
Abstract:
Polycyclic compounds that are aromatic or partially aromatic, and are substituted with one or more alkyl groups having an amino group and a carboxylic acid group, and includes carbon quantum dots (CQDs) that contain these compounds. The compounds and CQDs have a selective affinity for cells that express LAT1 and for tumor cells, and can internalize within such cells. The compounds and CQDs are useful for imaging of such cells and for delivering cargo compounds to and into cells that express LAT1 and tumor cells. Methods for making and using these compounds and CQDs for bioimaging and targeting certain tissues, including tumors, are disclosed.
Inventors:
FAN LOUZHEN (CN)
LI SHUHUA (CN)
SU WEN (CN)
WU HAO (CN)
LI SHUHUA (CN)
SU WEN (CN)
WU HAO (CN)
Application Number:
PCT/CN2019/115263
Publication Date:
May 14, 2021
Filing Date:
November 04, 2019
Export Citation:
Assignee:
UNIV BEIJING NORMAL (CN)
International Classes:
C09K11/06; B82B3/00; C09K11/02; C09K11/08; C09K11/65
Foreign References:
| CN110041923A | 2019-07-23 | |||
| KR20160014188A | 2016-02-11 | |||
| KR20160010744A | 2016-01-28 | |||
| CN104164232A | 2014-11-26 |
Attorney, Agent or Firm:
HAIHONG JIACHENG INTELLECTUAL PROPERTY & PARTNERS (CN)
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