Title:
CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/057932
Kind Code:
A1
Abstract:
A carbonyl heterocyclic compound as represented by formula II or a pharmaceutically acceptable salt thereof. The carbonyl heterocyclic compound can be used as a compound having a targeted lanthionine synthetase C-like protein 2 pathway; and the compound can be used for treating multiple conditions, including an infection disease, an autoimmune disease, diabetes, and a chronic inflammatory disease.
Inventors:
ZHANG CHAOXIN (CN)
XIA GUANGXIN (CN)
XIANG ZHIJUN (CN)
KE YING (CN)
LOU JIANGSONG (CN)
ZHAO MENGHAO (CN)
HAO LIJUN (CN)
XIA GUANGXIN (CN)
XIANG ZHIJUN (CN)
KE YING (CN)
LOU JIANGSONG (CN)
ZHAO MENGHAO (CN)
HAO LIJUN (CN)
Application Number:
PCT/CN2021/119427
Publication Date:
March 24, 2022
Filing Date:
September 18, 2021
Export Citation:
Assignee:
SHANGHAI PHARMACEUTICALS HOLDING CO LTD (CN)
International Classes:
C07D235/18; A61K31/4184; A61K31/44; A61P1/00; A61P3/10; A61P29/00; A61P31/12; A61P37/02; C07D401/14; C07D403/14; C07D413/14
Domestic Patent References:
| WO2021127472A1 | 2021-06-24 |
Foreign References:
| CN107108573A | 2017-08-29 | |||
| CN111511904A | 2020-08-07 |
Other References:
DATABASE REGISTRY 14 July 2020 (2020-07-14), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -2446108-98-9 REGISTRY ED -Entered STN: 14 Jul 2020 CN -4-Pyridinecarboxamide, 2-(1H-benzimidazol-2-yl)- (CA INDEX NAME)", XP055912830, retrieved from STN Database accession no. 2446108-98-9
DATABASE REGISTRY 7 December 2008 (2008-12-07), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -1081112-55-1 REGISTRY ED -Entered STN: 07 Dec 2008 CN -Benzamide, 3-(1H-benzimidazol-2-yl)- (CA INDEX NAME)", XP055912833, retrieved from STN Database accession no. 1081112-55-1
DATABASE REGISTRY 14 October 2003 (2003-10-14), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -603973-01-9 REGISTRY ED -Entered STN: 14 Oct 2003 CN -Benzamide, 3-imidazo[1,2-a]pyridin-2-yl- (CA INDEX NAME)", XP055912836, retrieved from STN Database accession no. 603973-01-9
DATABASE REGISTRY 16 November 1984 (1984-11-16), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -74356-82-4 REGISTRY ED -Entered STN: 16 Nov 1984 CN -2-Pyridinecarboxamide, 6-(1H-benzimidazol-2-yl)- (CA INDEX NAME)", XP055912837, retrieved from STN Database accession no. 74356-82-4
DATABASE REGISTRY 2 February 2011 (2011-02-02), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -1261353-08-5 REGISTRY ED -Entered STN: 02 Feb 2011 CN -Urea, N-[6-(4-morpholinyl)-2-pyridinyl]- (CA INDEX NAME)", XP055912865, retrieved from STN Database accession no. 1261353-08-5
DATABASE REGISTRY 14 December 2005 (2005-12-14), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -869861-35-8 REGISTRY ED -Entered STN: 14 Dec 2005 CN -Urea, N-[3-(4-morpholinyl)phenyl]- (CA INDEX NAME)", XP055912870, retrieved from STN Database accession no. 869861-35-8
DATABASE REGISTRY 15 October 2008 (2008-10-15), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -1061750-16-0 REGISTRY ED -Entered STN: 15 Oct 2008 CN -2-Pyridinecarboxamide, 6-(4-morpholinyl)- (CA INDEX NAME)", XP055912872, retrieved from STN Database accession no. 1061750-16-0
DATABASE REGISTRY 18 December 2008 (2008-12-18), ANONYMOUS: "4-Pyridinecarboxamide, 2-(4-morpholinyl)- (CA INDEX NAME)", XP055912873, retrieved from STN Database accession no. 1086397-58-1
DATABASE REGISTRY 28 November 1996 (1996-11-28), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -183557-81-5 REGISTRY ED -Entered STN: 28 Nov 1996 CN -Benzamide, 3-(4-morpholinyl)-(CA INDEX NAME)", XP055912875, retrieved from STN Database accession no. 183557-81-5
DATABASE REGISTRY 20 February 2019 (2019-02-20), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -2271173-02-3 REGISTRY ED -Entered STN: 20 Feb 2019 CN -Benzamide, 3-(diphenylamino)-(CA INDEX NAME)", XP055912880, retrieved from STN Database accession no. 2271173-02-3
DATABASE REGISTRY 23 May 2007 (2007-05-23), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -935688-08-7 REGISTRY ED -Entered STN: 23 May 2007 CN -Benzamide, 3-(phenylamino)-(CA INDEX NAME)", XP055912884, retrieved from STN Database accession no. 935688-08-7
DATABASE REGISTRY 1 December 2020 (2020-12-01), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -2539007-30-0 REGISTRY ED -Entered STN: 01 Dec 2020 CN -Urea, N-[3-(1H-benzimidazol-2-yl)phenyl]- (CA INDEX NAME)", XP055912886, retrieved from STN Database accession no. 2539007-30-0
DATABASE REGISTRY 7 December 2008 (2008-12-07), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -1081112-55-1 REGISTRY ED -Entered STN: 07 Dec 2008 CN -Benzamide, 3-(1H-benzimidazol-2-yl)- (CA INDEX NAME)", XP055912833, retrieved from STN Database accession no. 1081112-55-1
DATABASE REGISTRY 14 October 2003 (2003-10-14), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -603973-01-9 REGISTRY ED -Entered STN: 14 Oct 2003 CN -Benzamide, 3-imidazo[1,2-a]pyridin-2-yl- (CA INDEX NAME)", XP055912836, retrieved from STN Database accession no. 603973-01-9
DATABASE REGISTRY 16 November 1984 (1984-11-16), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -74356-82-4 REGISTRY ED -Entered STN: 16 Nov 1984 CN -2-Pyridinecarboxamide, 6-(1H-benzimidazol-2-yl)- (CA INDEX NAME)", XP055912837, retrieved from STN Database accession no. 74356-82-4
DATABASE REGISTRY 2 February 2011 (2011-02-02), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -1261353-08-5 REGISTRY ED -Entered STN: 02 Feb 2011 CN -Urea, N-[6-(4-morpholinyl)-2-pyridinyl]- (CA INDEX NAME)", XP055912865, retrieved from STN Database accession no. 1261353-08-5
DATABASE REGISTRY 14 December 2005 (2005-12-14), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -869861-35-8 REGISTRY ED -Entered STN: 14 Dec 2005 CN -Urea, N-[3-(4-morpholinyl)phenyl]- (CA INDEX NAME)", XP055912870, retrieved from STN Database accession no. 869861-35-8
DATABASE REGISTRY 15 October 2008 (2008-10-15), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -1061750-16-0 REGISTRY ED -Entered STN: 15 Oct 2008 CN -2-Pyridinecarboxamide, 6-(4-morpholinyl)- (CA INDEX NAME)", XP055912872, retrieved from STN Database accession no. 1061750-16-0
DATABASE REGISTRY 18 December 2008 (2008-12-18), ANONYMOUS: "4-Pyridinecarboxamide, 2-(4-morpholinyl)- (CA INDEX NAME)", XP055912873, retrieved from STN Database accession no. 1086397-58-1
DATABASE REGISTRY 28 November 1996 (1996-11-28), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -183557-81-5 REGISTRY ED -Entered STN: 28 Nov 1996 CN -Benzamide, 3-(4-morpholinyl)-(CA INDEX NAME)", XP055912875, retrieved from STN Database accession no. 183557-81-5
DATABASE REGISTRY 20 February 2019 (2019-02-20), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -2271173-02-3 REGISTRY ED -Entered STN: 20 Feb 2019 CN -Benzamide, 3-(diphenylamino)-(CA INDEX NAME)", XP055912880, retrieved from STN Database accession no. 2271173-02-3
DATABASE REGISTRY 23 May 2007 (2007-05-23), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -935688-08-7 REGISTRY ED -Entered STN: 23 May 2007 CN -Benzamide, 3-(phenylamino)-(CA INDEX NAME)", XP055912884, retrieved from STN Database accession no. 935688-08-7
DATABASE REGISTRY 1 December 2020 (2020-12-01), ANONYMOUS: "/1 -(C) FILE REGISTRY RN -2539007-30-0 REGISTRY ED -Entered STN: 01 Dec 2020 CN -Urea, N-[3-(1H-benzimidazol-2-yl)phenyl]- (CA INDEX NAME)", XP055912886, retrieved from STN Database accession no. 2539007-30-0
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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