Title:
CATIONIC LIPID COMPOUND
Document Type and Number:
WIPO Patent Application WO/2018/062233
Kind Code:
A1
Abstract:
The present invention provides a compound represented by formula (I), which is usable as a cationic lipid facilitating the introduction of a nucleic acid into a cell, or the like, and a composition, or the like, containing the compound.
Inventors:
HOSOE SHINTARO (JP)
YABUUCHI HAYATO (JP)
YABUUCHI HAYATO (JP)
Application Number:
PCT/JP2017/034878
Publication Date:
April 05, 2018
Filing Date:
September 27, 2017
Export Citation:
Assignee:
KYOWA HAKKO KIRIN CO LTD (JP)
International Classes:
C07C217/28; A61K31/7088; A61K31/713; A61K47/18; A61K48/00; A61P1/16; A61P11/00; A61P13/12; C12N15/113
Domestic Patent References:
| WO2012108397A1 | 2012-08-16 |
Foreign References:
| JP2013533223A | 2013-08-22 | |||
| JP2013531634A | 2013-08-08 | |||
| JPH09255638A | 1997-09-30 |
Other References:
ANTIPINA, MARIA N. ET AL.: "Investigation of the protonation state of novel cationic lipids designed for gene transfection", THE JOURNAL OF PHYSICAL CHEMISTRY B, vol. 111, no. 49, 2007, pages 13845 - 13850, XP055596814, ISSN: 1520-6106, DOI: 10.1021/jp0755591
KIM, JU HEE ET AL.: "A new dioleate compound from Callistemon lanceolatus", BULLETIN OF THE KOREAN CHEMICAL SOCIETY, vol. 33, no. 1, 2012, pages 344 - 346, XP055498371
See also references of EP 3521270A4
KIM, JU HEE ET AL.: "A new dioleate compound from Callistemon lanceolatus", BULLETIN OF THE KOREAN CHEMICAL SOCIETY, vol. 33, no. 1, 2012, pages 344 - 346, XP055498371
See also references of EP 3521270A4
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
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