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Title:
CD19-TARGETED CHIMERIC ANTIGEN RECEPTOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/121193
Kind Code:
A1
Abstract:
A chimeric antigen receptor, comprising an amino acid sequence shown in SEQ ID NO.1. A nucleic acid encoding the chimeric antigen receptor, a vector comprising the nucleic acid, an immune effector cell comprising the chimeric antigen receptor, the nucleic acid molecule and/or the vector, a method for preparing the immune effector cell, a composition comprising the immune effector cell, and use of the chimeric antigen receptor.

Inventors:
WANG JIANXIANG (CN)
WANG MIN (CN)
LV LULU (CN)
SHI LIN (CN)
AN NA (CN)
WANG RUI (CN)
LIU YUN (CN)
Application Number:
PCT/CN2020/136241
Publication Date:
June 24, 2021
Filing Date:
December 14, 2020
Export Citation:
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Assignee:
JUVENTAS CELL THERAPY LTD (CN)
International Classes:
C12N9/22; A61K48/00; C07K16/28; C07K19/00; C12N5/10; C12N15/63
Domestic Patent References:
WO2015036583A22015-03-19
Foreign References:
CN104788573A2015-07-22
CN110404061A2019-11-05
CN105431532A2016-03-23
CN105418765B2019-09-06
CN107827991A2018-03-23
US20180186878A12018-07-05
US20180325955A12018-11-15
Other References:
"UniProt/Swiss-Prot", Database accession no. P15391
ALTSCHUL ET AL., J.MOL. BIOL., vol. 215, 1990, pages 403
SAMBROOK, J.FRITSCH, E. F.MANIAIS, T.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
See also references of EP 4032978A4
Attorney, Agent or Firm:
SHANGHAI DIANSHI PARTNERS, P.C. (CN)
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