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Title:
CD4+ AND/OR CD8+ CELL POPULATIONS COMPRISING ICARS FOR USE IN TREATMENT THERAPIES
Document Type and Number:
WIPO Patent Application WO/2023/076912
Kind Code:
A3
Abstract:
The invention relates to the field of cancer immunotherapy by employing CD4+ cell populations, CD8+ cell populations, or a combination thereof, comprising bicistronic inhibitory chimeric antigen receptor (iCAR)/activating chimeric antigen receptor (aCAR) constructs for use in cancer treatment therapies.

Inventors:
WEIST MICHAEL (US)
SCHNAIR CAITLIN (US)
Application Number:
PCT/US2022/078671
Publication Date:
June 08, 2023
Filing Date:
October 25, 2022
Export Citation:
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Assignee:
IMMPACT BIO USA INC (US)
International Classes:
A61K35/17; C07K16/30; A61P35/00; C07K14/725
Domestic Patent References:
WO2019068007A12019-04-04
WO2022051727A22022-03-10
WO2021173985A22021-09-02
WO2020065406A22020-04-02
Foreign References:
US20200283529A12020-09-10
US20210292389A12021-09-23
US20210230247A12021-07-29
US20190216851A12019-07-18
Attorney, Agent or Firm:
CAVAZOS, Alexandra et al. (US)
Download PDF:
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