Title:
CELL CULTURE SUBSTRATE AND MANUFACTURING METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/133143
Kind Code:
A1
Abstract:
A cell culture substrate is provided. A cell culture substrate according to an embodiment of the present invention comprises: a fibrous web in which fibers are integrated; and a cell culture coating layer comprising a coating film connecting at least some fibers from among fibers positioned on one surface of the fibrous web, wherein the cell culture coating layer is realized through a fusion protein for cell culture in which a functional peptide is bound to a mussel adhesive protein. Thus, the substrate can be stored at room temperature for a long period of time, i.e., several years, despite containing protein-like substances that aid in cell culture, and thus exhibits very high storage stability. At the same time, the activity of substances that aid in cell culture is maintained at the same level or is reduced only minimally, thus enabling cell culture at an initially designed level. In addition, the cell culture substrate has excellent cell adhesion and can stably proliferate adhered cells, and thus can achieve high cell culture efficiency, and accordingly, can be widely applied to the culture of various cells such as stem cells.
Inventors:
KIM HYEONG TAEK (KR)
SEO DONG SIK (KR)
GOO HUI GWAN (KR)
SEO DONG SIK (KR)
GOO HUI GWAN (KR)
Application Number:
PCT/KR2020/019215
Publication Date:
July 01, 2021
Filing Date:
December 28, 2020
Export Citation:
Assignee:
AMOLIFESCIENCE CO LTD (KR)
International Classes:
C12M1/00; C12M1/12; C12N5/00
Domestic Patent References:
| WO2019013580A1 | 2019-01-17 |
Foreign References:
| KR20170132994A | 2017-12-05 | |||
| KR20140053903A | 2014-05-08 | |||
| JP2017147951A | 2017-08-31 | |||
| KR20170135769A | 2017-12-08 |
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
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