Title:
CELL CULTURE SUBSTRATE
Document Type and Number:
WIPO Patent Application WO/2018/116904
Kind Code:
A1
Abstract:
The invention provides a cell culture substrate comprising a block polymer of a segment having a lower critical solution temperature and a hydrophobic segment, the cell culture substrate being characterized in that an adhesive substrate is further included in the cell culture substrate, and the adhesive substrate is an extracellular matrix and/or an adhesive synthetic substrate. Also provided is a cell culture substrate wherein said extracellular matrix is at least one type selected from laminin, fibronectin, vitronectin, cadherin and fragments thereof, and/or, said adhesive synthetic substrate is poly[2-(methacryloyloxy)ethyl dimethyl-(3-sulfopropyl) ammonium hydroxide] or an oligopeptide-supporting polymer.
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Inventors:
NAKAGUMA HIROHIDE (JP)
TAKADA TETSUO (JP)
ISSHIKI AYAKO (JP)
TAKADA TETSUO (JP)
ISSHIKI AYAKO (JP)
Application Number:
PCT/JP2017/044508
Publication Date:
June 28, 2018
Filing Date:
December 12, 2017
Export Citation:
Assignee:
DAINIPPON INK & CHEMICALS (JP)
International Classes:
C12M3/00; C08F293/00; C12N5/10
Domestic Patent References:
| WO2015093393A1 | 2015-06-25 | |||
| WO2016199552A1 | 2016-12-15 | |||
| WO2011043405A1 | 2011-04-14 | |||
| WO2014199754A1 | 2014-12-18 |
Foreign References:
| JP2013195399A | 2013-09-30 | |||
| JP2014140384A | 2014-08-07 | |||
| US20110033928A1 | 2011-02-10 |
Other References:
MELLATI A.: "Influence of polymer molecular weight on the in vitro cytotoxicity of poly (N-isopropylacrylamide)", MATERIALS SCIENCE AND ENGINEERING C, vol. 59, 22 October 2015 (2015-10-22), pages 509 - 513, XP029329711, ISSN: 0928-4931, DOI: 10.1016/j.msec.2015.10.043
See also references of EP 3561043A4
See also references of EP 3561043A4
Attorney, Agent or Firm:
KONO Michihiro (JP)
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