Title:
CELL-DEATH INHIBITOR, AND PRODUCTION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2014/136808
Kind Code:
A1
Abstract:
Provided is a cell-death inhibitor including, as an active ingredient thereof, a compound represented by formula (1), and/or a compound represented by formula (2). The cell-death inhibitor exhibits high cell-death inhibition activity.
Inventors:
SATOH AYANO (JP)
NISHINA YUTA (JP)
NISHINA YUTA (JP)
Application Number:
PCT/JP2014/055533
Publication Date:
September 12, 2014
Filing Date:
March 05, 2014
Export Citation:
Assignee:
UNIV OKAYAMA NAT UNIV CORP (JP)
International Classes:
A61K31/404; A61K31/423; A61P1/16; A61P9/10; A61P43/00; C07D209/12; C07D209/14; C07D263/56; C07B61/00
Domestic Patent References:
| WO2001074807A1 | 2001-10-11 |
Other References:
SIBGATULIN,D.A. ET AL.: "Reaction of enamines with trifluoromethyl containing carbonyl reagents", JOURNAL OF FLUORINE CHEMISTRY, vol. 131, no. 2, 2010, pages 190 - 199, XP026871302
KAWASE, M. ET AL.: "Alpha-trifluoromethylated acyloins induce apoptosis in human oral tumor cell lines", BIOORG MED CHEM LETT, vol. 9, no. 21, 1999, pages 3113 - 8, XP004181017, DOI: doi:10.1016/S0960-894X(99)00548-X
KAWASE, M. ET AL.: "Alpha-trifluoromethylated acyloins induce apoptosis in human oral tumor cell lines", BIOORG MED CHEM LETT, vol. 9, no. 21, 1999, pages 3113 - 8, XP004181017, DOI: doi:10.1016/S0960-894X(99)00548-X
Attorney, Agent or Firm:
NAKATSUKASA, Shigeki et al. (JP)
Shigeki Nakamu (JP)
Shigeki Nakamu (JP)
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