CELL LOCATION UNIT, ARRAY, DEVICE AND FORMATION METHOD THEREOF

Title:

CELL LOCATION UNIT, ARRAY, DEVICE AND FORMATION METHOD THEREOF

Document Type and Number:

WIPO Patent Application WO/2015/196957

Kind Code:

A1

Abstract:

Disclosed is a cell location unit (100), array, device and a formation method thereof, wherein the cell location unit (100) comprises a substrate (110), and at least one pair of microelectrodes (120-1, 120-2, 130-1, 130-2) on the substrate (110). The microelectrodes (120-1, 120-2, 130-1, 130-2) are distributed along a circle at intervals, so as to generate positive a dielectrophoresis force area at an end aggregation area of the microelectrodes. A voltage signal of at least one microelectrode connection and a voltage signal of another microelectrode connection have a phase difference. A cell location hole (140) is located on a microelectrode, the accommodation space of which exposes the positive dielectrophoresis force area and accommodates individual cells (150). Cells are moved to the surface of the electrodes by applying the AC signal with a specific amplitude, frequency and phase to the microelectrodes. Individual cells are precisely located in a specific position by coordinating the cell location hole with the microelectrodes.

Inventors:

HUANG CHENGJUN (CN)
LUO JUN (CN)
ZHAO CHAO (CN)

Application Number:

PCT/CN2015/082034

Publication Date:

December 30, 2015

Filing Date:

June 23, 2015

Export Citation:

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Assignee:

BASETRA MEDICAL TECHNOLOGY CO LTD (CN)

International Classes:

C12M1/42; B03C5/00

Foreign References:

US20040112748A1	2004-06-17
US5858192A	1999-01-12
CN101580797A	2009-11-18
CN102296028A	2011-12-28
CN102321536A	2012-01-18
CN103074212A	2013-05-01

Other References: