Title:
CELL PRODUCTION METHOD
Document Type and Number:
WIPO Patent Application WO/2019/189545
Kind Code:
A1
Abstract:
As a technique for producing cells each having a desired substance introduced therein in a large quantity on a commercial scale, a production method is provided, which comprises a step of forming aggregates of cells in a cell-nonattachable container under conditions where the transfection of a substance into cells can be achieved.
Inventors:
YOSHIDA YOSHINORI (JP)
MIKI KENJI (JP)
KAMACHI YASUHARU (JP)
MIKI KENJI (JP)
KAMACHI YASUHARU (JP)
Application Number:
PCT/JP2019/013518
Publication Date:
October 03, 2019
Filing Date:
March 28, 2019
Export Citation:
Assignee:
UNIV KYOTO (JP)
TAKEDA PHARMACEUTICALS CO (JP)
TAKEDA PHARMACEUTICALS CO (JP)
International Classes:
C12N5/10; C12N15/85
Domestic Patent References:
| WO2015141827A1 | 2015-09-24 | |||
| WO2015141827A1 | 2015-09-24 | |||
| WO2007069666A1 | 2007-06-21 | |||
| WO2008118220A2 | 2008-10-02 | |||
| WO2008124133A1 | 2008-10-16 | |||
| WO2008151058A2 | 2008-12-11 | |||
| WO2009006930A1 | 2009-01-15 | |||
| WO2009006997A1 | 2009-01-15 | |||
| WO2009007852A2 | 2009-01-15 | |||
| WO2015105172A1 | 2015-07-16 | |||
| WO2005033298A1 | 2005-04-14 | |||
| WO2007002136A2 | 2007-01-04 | |||
| WO2007126077A1 | 2007-11-08 | |||
| WO2009118928A1 | 2009-10-01 |
Foreign References:
| JP2015515859A | 2015-06-04 | |||
| JP2008532480A | 2008-08-21 | |||
| JP2008307007A | 2008-12-25 | |||
| JP2008283972A | 2008-11-27 | |||
| US20080236610A1 | 2008-10-02 | |||
| US20090047263A1 | 2009-02-19 |
Other References:
HSU C. Y. ET AL.: "Non-viral transfection of primary human fibroblasts in suspension microcarrier culture", MOL. THER., vol. 24, no. 1, May 2016 (2016-05-01), pages S137 - S138, XP055638815
LI B. ET AL.: "Engineering human ventricular heart muscles based on a highly efficient system for purification of human pluripotent stem cell -derived ventricular cardiomyocytes", STEM CELL RES. THER., vol. 8, no. 1, 29 September 2017 (2017-09-29), pages 202, XP055638819
MIKI ET AL.: "Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches", CELL STEM CELL, vol. 16, 2015, pages 1 - 13
TAKAHASHI KYAMANAKA S, CELL, vol. 126, 2006, pages 663 - 676
TAKAHASHI KYAMANAKA S ET AL., CELL, vol. 131, 2007, pages 861 - 872
OKITA, K.ICHISAKA, T.YAMANAKA, S., NATURE, vol. 451, 2007, pages 141 - 146
HUANGFU D.MELTON, DA. ET AL., NATURE BIOTECHNOLOGY, vol. 26, no. 7, 2008, pages 795 - 797
OKITA K ET AL., NAT. METHODS, vol. 8, no. 5, May 2011 (2011-05-01), pages 409 - 12
OKITA K ET AL., STEM CELLS, vol. 31, no. 3, pages 458 - 66
YU J.THOMSON JA. ET AL., SCIENCE, vol. 318, 2007, pages 1917 - 1920
SHI Y.DING S. ET AL., CELL STEM CELL, vol. 3, 2008, pages 568 - 574
KIM JB.SCHOLER HR. ET AL., NATURE, vol. 454, 2008, pages 646 - 650
B. WEFERS ET AL., NATURE PROTOCOLS, vol. 8, no. 12, 2013, pages 2355 - 2379
T. SAKUMA ET AL., NATURE PROTOCOLS, vol. 11, no. 1, 2016, pages 118 - 133
"NCBI", Database accession no. NM 001164171
LAFLAMME MA ET AL.: "Nature", 2011, LAFLAMME MA MURRY CE
WARREN L ET AL., CELL STEM CELL, vol. 7, no. 5, 2010, pages 618 - 30
See also references of EP 3778902A4
LI B. ET AL.: "Engineering human ventricular heart muscles based on a highly efficient system for purification of human pluripotent stem cell -derived ventricular cardiomyocytes", STEM CELL RES. THER., vol. 8, no. 1, 29 September 2017 (2017-09-29), pages 202, XP055638819
MIKI ET AL.: "Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches", CELL STEM CELL, vol. 16, 2015, pages 1 - 13
TAKAHASHI KYAMANAKA S, CELL, vol. 126, 2006, pages 663 - 676
TAKAHASHI KYAMANAKA S ET AL., CELL, vol. 131, 2007, pages 861 - 872
OKITA, K.ICHISAKA, T.YAMANAKA, S., NATURE, vol. 451, 2007, pages 141 - 146
HUANGFU D.MELTON, DA. ET AL., NATURE BIOTECHNOLOGY, vol. 26, no. 7, 2008, pages 795 - 797
OKITA K ET AL., NAT. METHODS, vol. 8, no. 5, May 2011 (2011-05-01), pages 409 - 12
OKITA K ET AL., STEM CELLS, vol. 31, no. 3, pages 458 - 66
YU J.THOMSON JA. ET AL., SCIENCE, vol. 318, 2007, pages 1917 - 1920
SHI Y.DING S. ET AL., CELL STEM CELL, vol. 3, 2008, pages 568 - 574
KIM JB.SCHOLER HR. ET AL., NATURE, vol. 454, 2008, pages 646 - 650
B. WEFERS ET AL., NATURE PROTOCOLS, vol. 8, no. 12, 2013, pages 2355 - 2379
T. SAKUMA ET AL., NATURE PROTOCOLS, vol. 11, no. 1, 2016, pages 118 - 133
"NCBI", Database accession no. NM 001164171
LAFLAMME MA ET AL.: "Nature", 2011, LAFLAMME MA MURRY CE
WARREN L ET AL., CELL STEM CELL, vol. 7, no. 5, 2010, pages 618 - 30
See also references of EP 3778902A4
Attorney, Agent or Firm:
OHNO Seiji et al. (JP)
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