Title:
CELLS CAPABLE OF DIFFERENTIATING INTO MYOCARDIUM-LIKE CELLS
Document Type and Number:
WIPO Patent Application WO/2003/074684
Kind Code:
A1
Abstract:
Myocardial precursor cells and myocardium-like cells which can be obtained from muscles without using embryonic stem cells or bone marrow cells and are usable in: (a) identifying and evaluating a gene relating to myocardium differentiation and regeneration; (b) transplanting cells in the case of a heart disease; (c) searching for and evaluating a compound promoting myocardium differentiation; (d) searching for and evaluating a drug elevating cell transplantation efficiency (fixation of grafted cells into a biological tissue and promotion of the function thereof); and (e) constructing a model animal for developing a preventive/a remedy for a heart disease. Compounds obtained by the above searching are usable as safe preventives and remedies for heart diseases.
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Inventors:
INUZUKA HIROYUKI (JP)
TAKIZAWA MASAYUKI (JP)
KOYAMA NOBUYUKI (JP)
NOGUCHI KENICHI (JP)
TAKIZAWA MASAYUKI (JP)
KOYAMA NOBUYUKI (JP)
NOGUCHI KENICHI (JP)
Application Number:
PCT/JP2003/002647
Publication Date:
September 12, 2003
Filing Date:
March 06, 2003
Export Citation:
Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
INUZUKA HIROYUKI (JP)
TAKIZAWA MASAYUKI (JP)
KOYAMA NOBUYUKI (JP)
NOGUCHI KENICHI (JP)
INUZUKA HIROYUKI (JP)
TAKIZAWA MASAYUKI (JP)
KOYAMA NOBUYUKI (JP)
NOGUCHI KENICHI (JP)
International Classes:
A61P9/04; A61P9/10; A61P43/00; C12N5/077; G01N33/50; A61K35/12; (IPC1-7): C12N5/06; A01K67/027; A61K35/34; A61K45/00; A61P9/04; A61P9/10; A61P43/00; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50
Domestic Patent References:
| WO2000017326A1 | 2000-03-30 | |||
| WO2001011011A2 | 2001-02-15 | |||
| WO2001021767A2 | 2001-03-29 |
Attorney, Agent or Firm:
Takahashi, Shuichi c/o Osaka Plant of TAKEDA CHEMICAL INDUSTRIES LTD. (17-85, Jusohonmachi 2-chome, Yodogawa-k, Osaka-shi Osaka, JP)
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