Title:
CEPHALOSPORIN ANTIBACTERIAL COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/147986
Kind Code:
A1
Abstract:
Provided are a cephalosporin compound represented by formula I-1, I-2, or I-3, a pharmaceutical composition comprising same, and use thereof as an antibacterial agent.
Inventors:
HUANG JIAN (CN)
ZHU LINGJIAN (CN)
ZOU YANG (CN)
ZHANG CILI (CN)
ZHU LINGJIAN (CN)
ZOU YANG (CN)
ZHANG CILI (CN)
Application Number:
PCT/CN2021/073242
Publication Date:
July 29, 2021
Filing Date:
January 22, 2021
Export Citation:
Assignee:
SHANGHAI SENHUI MEDICINE CO LTD (CN)
SHANGHAI SHENGDI PHARMACEUTICAL CO LTD (CN)
JIANGSU HENGRUI MEDICINE CO (CN)
SHANGHAI SHENGDI PHARMACEUTICAL CO LTD (CN)
JIANGSU HENGRUI MEDICINE CO (CN)
International Classes:
C07D501/46; A61K31/546; A61P31/04
Domestic Patent References:
| WO2010050468A1 | 2010-05-06 | |||
| WO2017216765A1 | 2017-12-21 | |||
| WO2016035847A1 | 2016-03-10 |
Foreign References:
| CN102203100A | 2011-09-28 | |||
| CN105073759A | 2015-11-18 | |||
| JP2016079098A | 2016-05-16 | |||
| CN102918047A | 2013-02-06 | |||
| CN104039152A | 2014-09-10 | |||
| CN102918048A | 2013-02-06 | |||
| JP2015221788A | 2015-12-10 | |||
| EP0416410B1 | 1994-11-30 | |||
| CN106661052A | 2017-05-10 |
Other References:
AOKI TOSHIAKI; YOSHIZAWA HIDENORI; YAMAWAKI KENJI; YOKOO KATSUKI; SATO JUN; HISAKAWA SHINYA; HASEGAWA YASUSHI; KUSANO HIROKI; SANO: "Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities againstPseudomonas aeruginosaand other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 155, 8 June 2018 (2018-06-08), AMSTERDAM, NL, pages 847 - 868, XP085431301, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2018.06.014
ANTIMICROB AGENTS CHEMOTHER, vol. 22, no. 2, 1982, pages 181 - 185
EUR. J MED. CHEM., vol. 155, 2018, pages 847 - 868
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 155, 2018, pages 847 - 868
J. MED. CHEM., vol. 40, 1997, pages 1186 - 1194
ANTIMICROB AGENTS CHEMOTHER, vol. 22, no. 2, 1982, pages 181 - 185
EUR. J MED. CHEM., vol. 155, 2018, pages 847 - 868
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 155, 2018, pages 847 - 868
J. MED. CHEM., vol. 40, 1997, pages 1186 - 1194
Attorney, Agent or Firm:
GE CHENG & CO., LTD (CN)
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