Title:
CHEMICAL COMPOSITION OF TXS-WX COMPOUNDS, PREPARATION METHOD AND USE OF SAME AGAINST TUMORS
Document Type and Number:
WIPO Patent Application WO/2019/205180
Kind Code:
A1
Abstract:
Disclosed is a class of new type innate immune pathway activators (TXS－WX). The activator compounds can activate immune cells (dendritic cells, CD8 T-cells, etc.) by effectively activating the immune pathway, and can regulate the function of macrophages and change the microenvironment of tumors, thereby achieving a good immunological anti-tumor efficacy. The compounds are prepared by means of a comprehensive method of organic chemical synthesis combined with biosynthesis.
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Inventors:
TAN XIANGSHI (CN)
WU PEIJIAN (CN)
WANG XIANG (CN)
ZHANG YUERU (CN)
TAN YING HIN (CN)
WU PEIJIAN (CN)
WANG XIANG (CN)
ZHANG YUERU (CN)
TAN YING HIN (CN)
Application Number:
PCT/CN2018/085216
Publication Date:
October 31, 2019
Filing Date:
April 29, 2018
Export Citation:
Assignee:
HANGZHOU XINGAO BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07H21/00; A61K31/7084; A61P35/00
Domestic Patent References:
| WO2017027646A1 | 2017-02-16 | |||
| WO2017161349A1 | 2017-09-21 |
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