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Title:
CHEMOKINE RECEPTOR ACTIVITY REGULATOR
Document Type and Number:
WIPO Patent Application WO/2013/031931
Kind Code:
A1
Abstract:
Provided is a chemokine receptor activity regulator, etc. containing as the effective component thereof a pyrazolopyrimidine derivative indicated by formula (I) or a pharmaceutically acceptable salt thereof {in the formula, R1 indicates -NR1aR1b (in the formula, R1a and R1b are the same or different, and indicate a hydrogen atom, an aralkyl, etc.), R2 indicates (II) [in the formula, k and m each indicate an integer between 0 and 2, n indicates an integer between 0 and 2, L indicates a single bond, etc., R5 indicates halogen, etc., R6 indicates aryl, etc., x indicates -CR8 (in the formula, R8 indicates a hydrogen atom, etc.), etc., R7 indicates a hydrogen atom, etc.,] etc., R3 indicates -SO2R13 [in the formula, R13 indicates a lower alkoxy, -NR13d(C=0)R13e (in the formula, R13d indicates a hydrogen atom, etc., R13e indicates a lower alkyl, etc.,) etc.,] and R4 indicates a hydrogen atom, etc.}.

Inventors:
YAMAMOTO KEISUKE (JP)
ARATAKE SEIJI (JP)
HEMMI KAZUKI (JP)
MIZUTANI MIRAI (JP)
SENO YUKO (JP)
Application Number:
PCT/JP2012/072104
Publication Date:
March 07, 2013
Filing Date:
August 31, 2012
Export Citation:
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Assignee:
KYOWA HAKKO KIRIN CO LTD (JP)
YAMAMOTO KEISUKE (JP)
ARATAKE SEIJI (JP)
HEMMI KAZUKI (JP)
MIZUTANI MIRAI (JP)
SENO YUKO (JP)
International Classes:
A61K31/5377; A61K31/519; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P17/10; A61P29/00; A61P37/08; A61P43/00; C07D487/04; C07D519/00; C12N15/09
Domestic Patent References:
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WO2000059908A22000-10-12
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WO2000044754A12000-08-03
WO2009041663A12009-04-02
WO2003087366A12003-10-23
Foreign References:
JP2009007341A2009-01-15
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Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
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