CHITIN BEADS, CHITOSAN BEADS, PROCESSES FOR PRODUCING THESE BEADS, CARRIERS MADE OF THESE BEADS AND PROCESSES FOR PRODUCING MICROSPRODIDIAN SPORES

Title:

CHITIN BEADS, CHITOSAN BEADS, PROCESSES FOR PRODUCING THESE BEADS, CARRIERS MADE OF THESE BEADS AND PROCESSES FOR PRODUCING MICROSPRODIDIAN SPORES

Document Type and Number:

WIPO Patent Application WO/1998/051712

Kind Code:

A1

Abstract:

Chitin beads having a uniform fine particle size and made of microsporidian spores containing chitin as the major cell wall constituent; and chitosan beads having a uniform fine particle size and obtained by N-deacetylating the above chitin. Microsporidian spores are proliferated in insects or cultured cells to give the above-mentioned chitin beads. The chitosan beads are obtained by N-deacetylating the chitin. When the insects are domesticated silkworm larvae, 5 x 10?2� to 5 x 10?8�/ml of microsporidian spores are orally or percutaneously inoculated into the larvae of second-instar exuviated domesticated silkworm and proliferated therein. Then the spores thus proliferated are taken out of the larvae of fifth-instar domesticated silkworm and purified to give chitin beads with a uniform small particle size from which chitosan beads can be obtained as described above. These beads are used as carriers for immobilizing or encapsulating various substances such as antibiotics and microorganisms therein.

Inventors:

TSUKADA MASUHIRO
SHIRATA AKIRA
HAYASAKA SHOJI

Application Number:

PCT/JP1998/002112

Publication Date:

November 19, 1998

Filing Date:

May 13, 1998

Export Citation:

Click for automatic bibliography generation Help

Assignee:

JP NATIONAL INST OF SERICULTUR (JP)

International Classes:

A01N25/10; A01N25/26; C08B37/08; A23L5/00; A23L27/00; A23L29/275; A61K9/16; C09B67/02; (IPC1-7): C08B37/08

Foreign References:

JPH0977803A	1997-03-25
JPS62151430A	1987-07-06
JPS62151403A	1987-07-06

Other References: