Title:
CHITIN-BINDING POLYPEPTIDE, AND DETECTION METHOD AND DETECTION KIT FOR CHITIN
Document Type and Number:
WIPO Patent Application WO/2023/074415
Kind Code:
A1
Abstract:
The present invention pertains to a polypeptide which (a) is composed of an amino acid sequence A which shares a sequence identity of at least 80 % with the amino acid sequence represented by SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, or SEQ ID NO: 6, and which (b) has chitin-binding activity but does not exhibit chitin-degrading activity.
Inventors:
YAMANAKA DAISUKE (JP)
KIMURA MASAHIRO (JP)
ADACHI YOSHIYUKI (JP)
OYAMA FUMITAKA (JP)
KIMURA MASAHIRO (JP)
ADACHI YOSHIYUKI (JP)
OYAMA FUMITAKA (JP)
Application Number:
PCT/JP2022/038419
Publication Date:
May 04, 2023
Filing Date:
October 14, 2022
Export Citation:
Assignee:
TOKYO UNIV OF PHARMACY & LIFE SCIENCES (JP)
UNIV KOGAKUIN (JP)
UNIV KOGAKUIN (JP)
International Classes:
C12N15/10; C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/24; C12N15/56; G01N33/68
Domestic Patent References:
| WO2012111810A1 | 2012-08-23 |
Foreign References:
| JP2002505882A | 2002-02-26 |
Other References:
OKAWA KAZUAKI, OHNO MISA, KASHIMURA AKINORI, KIMURA MASAHIRO, KOBAYASHI YUKI, SAKAGUCHI MASAYOSHI, SUGAHARA YASUSATO, KAMAYA MINOR: "Loss and Gain of Human Acidic Mammalian Chitinase Activity by Nonsynonymous SNPs", MOLECULAR BIOLOGY AND EVOLUTION, vol. 33, no. 12, 1 December 2016 (2016-12-01), US , pages 3183 - 3193, XP093060995, ISSN: 0737-4038, DOI: 10.1093/molbev/msw198
FUSETTI FABRIZIA ET AL: "Structure of human chitotriosidase: Implications for specific inhibitor design and function of mammalian chitinase-like lectins", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 28, 12 July 2002 (2002-07-12), US , pages 25537 - 25544, XP002521255, ISSN: 0021-9258, DOI: 10.1074/jbc.m201636200
SIERECKI EMMA: "A Novel Split Reporter Uncages New Possibilities", ACS CENTRAL SCIENCE, vol. 5, no. 11, 27 November 2019 (2019-11-27), pages 1744 - 1746, XP055783415, ISSN: 2374-7943, DOI: 10.1021/acscentsci.9b01051
FUSETTI FABRIZIA ET AL: "Structure of human chitotriosidase: Implications for specific inhibitor design and function of mammalian chitinase-like lectins", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 28, 12 July 2002 (2002-07-12), US , pages 25537 - 25544, XP002521255, ISSN: 0021-9258, DOI: 10.1074/jbc.m201636200
SIERECKI EMMA: "A Novel Split Reporter Uncages New Possibilities", ACS CENTRAL SCIENCE, vol. 5, no. 11, 27 November 2019 (2019-11-27), pages 1744 - 1746, XP055783415, ISSN: 2374-7943, DOI: 10.1021/acscentsci.9b01051
Attorney, Agent or Firm:
ONO Makoto et al. (JP)
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