Title:
CLASS OF CDK INHIBITOR BASED ON ORGANIC ARSINE, PREPARATION METHOD AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/057867
Kind Code:
A1
Abstract:
Provided is a class of CDK inhibitor based on organic arsine, a preparation method, and an application thereof. Specifically, provided is a compound represented by formula I, a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a hydrate, or a solvate thereof. Also provided is a preparation method and an application thereof. Each group in the formula is as defined in the specification.
Inventors:
TAN LI (CN)
LI YING (CN)
ZHOU SHAOQING (CN)
ZHUANG GUANGLEI (CN)
LI YING (CN)
ZHOU SHAOQING (CN)
ZHUANG GUANGLEI (CN)
Application Number:
PCT/CN2020/117550
Publication Date:
April 01, 2021
Filing Date:
September 24, 2020
Export Citation:
Assignee:
SHANGHAI INST ORGANIC CHEMISTRY CAS (CN)
International Classes:
C07F9/80; A61P35/00; C07F9/74
Domestic Patent References:
| WO2005034935A1 | 2005-04-21 |
Foreign References:
| CN109369724A | 2019-02-22 | |||
| CN107814796A | 2018-03-20 | |||
| CN103756630A | 2014-04-30 | |||
| US2772303A | 1956-11-27 | |||
| CN1742100A | 2006-03-01 | |||
| CN1589149A | 2005-03-02 |
Other References:
W LEE LEWIS , H E BENT: "A study of 3, 4-diamino-phenylarsonic acid and some of its derivatives", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 48, 5 April 1926 (1926-04-05), pages 949 - 957, XP055795171
WALTER A JACOBS , MICHAEL HEIDELBERGER: "Aromatic arsenic compounds.V. N-substituted glycylarsanilic acids", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 41, 31 December 1919 (1919-12-31), pages 1809 - 1821, XP055795180
WALTER A JACOBS , MICHAEL HEIDELBERGER: "Aromatic arsenic compounds.V. N-substituted glycylarsanilic acids", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 41, 31 December 1919 (1919-12-31), pages 1809 - 1821, XP055795180
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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