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Title:
A CLASS OF NEW TYPE SGLT2 INHIBITOR COMPOUND AND A PHARMACEUTICAL COMPOSITION THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/070740
Kind Code:
A1
Abstract:
The present invention discloses a class of a compound shown by general formula (I), a pharmaceutically acceptable salt thereof, an easily hydrolyzed prodrug ester or an isomer thereof, a pharmaceutical composition containing this class of compounds as an inhibitor of sodium-glucose cotransporter 2 (SGLT2), for treating or delaying diabetes, diabetic retinopathy, diabetic neuropathy, diabetic nephropathy, insulin resistance, hyperglycemia, hyperinsulinemia, rising fatty acid or glycerin, hyperlipidemia, obesity, hypertriglyceridemia, X syndrome, diabetic complication, atherosclerosis or hypertension etc. and related diseases.

Inventors:
SHI DONGFANG (CN)
FU CHANGJIN (CN)
JIANG QIANGHUA (CN)
LIU WEI (CN)
ZHANG CHANGLIANG (CN)
Application Number:
PCT/CN2015/093100
Publication Date:
May 12, 2016
Filing Date:
October 28, 2015
Export Citation:
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Assignee:
ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D421/10; A61K31/351; A61K31/7042; C07H1/00; C07H15/26
Domestic Patent References:
WO2012140120A12012-10-18
WO2012041898A12012-04-05
WO2013064909A22013-05-10
WO2011159067A22011-12-22
Foreign References:
CN104817554A2015-08-05
CN104672227A2015-06-03
Attorney, Agent or Firm:
NANJING TIANHUA PATENT AGENT CO., LTD. (CN)
南京天华专利代理有限责任公司 (CN)
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