Title:
CLONIDINE-CONTAINING ADHESIVE PATCH
Document Type and Number:
WIPO Patent Application WO/2015/087755
Kind Code:
A1
Abstract:
An adhesive patch for local pain relief, which is provided with a supporting body and an adhesive layer that is laminated on the supporting body. The adhesive layer contains clonidine or a pharmaceutically acceptable salt thereof, a skin permeation suppressant for clonidine or a pharmaceutically acceptable salt thereof, and an adhesive. The skin permeation suppressant for clonidine or a pharmaceutically acceptable salt thereof is composed of at least one substance selected from the group consisting of citric acid, oleic acid, stearic acid, isostearic acid, malic acid, lactic acid, a copolymer of methacrylic acid and a methacrylic acid ester, and a polyethylene glycol. The content of clonidine or a pharmaceutically acceptable salt thereof is 0.9% by mass or less based on the total mass of the adhesive layer.
Inventors:
YASUKOCHI TAKASHI (JP)
YAMAMOTO NAOKI (JP)
YAMAMOTO NAOKI (JP)
Application Number:
PCT/JP2014/081970
Publication Date:
June 18, 2015
Filing Date:
December 03, 2014
Export Citation:
Assignee:
HISAMITSU PHARMACEUTICAL CO (JP)
International Classes:
A61K31/4168; A61K9/70; A61K47/12; A61K47/32; A61K47/34; A61P29/00
Foreign References:
| JPH05503539A | 1993-06-10 | |||
| JPS58190444A | 1983-11-07 | |||
| JPH01287024A | 1989-11-17 | |||
| JP2012140407A | 2012-07-26 | |||
| JPS60199834A | 1985-10-09 | |||
| JP2011020997A | 2011-02-03 | |||
| JPH04103528A | 1992-04-06 |
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
Yoshiki Hasegawa (JP)
Yoshiki Hasegawa (JP)
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