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Title:
CO-CRYSTAL OF ELACESTRANT DIHYDROCHLORIDE, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/104268
Kind Code:
A1
Abstract:
The present invention relates to a co-crystal of elacestrant (hereinafter referred to as "compound (I)") dihydrochloride and a preparation method therefor, a pharmaceutical composition comprising the co-crystal, and a use of the co-crystal in the preparation of an estrogen receptor degradation agent drug and a drug for treating estrogen receptor positive breast cancers or human epidermal growth factor receptor 2 negative breast cancers.

Inventors:
ZHANG YUXING (CN)
ZHANG JING (CN)
MENG LIPING (CN)
Application Number:
PCT/CN2023/130967
Publication Date:
May 23, 2024
Filing Date:
November 10, 2023
Export Citation:
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Assignee:
CRYSTAL PHARMACEUTICAL SUZHOU CO LTD (CN)
International Classes:
C07C217/84; A61K31/137; A61P35/00
Domestic Patent References:
WO2023064519A12023-04-20
WO2016176665A12016-11-03
Foreign References:
CN112423844A2021-02-26
CN110191707A2019-08-30
US20060116364A12006-06-01
CN113348163A2021-09-03
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