COATING LIQUID FOR MICRONEEDLES, MICRONEEDLE-COATING SUBSTANCE, AND MICRONEEDLE ARRAY

Title:

COATING LIQUID FOR MICRONEEDLES, MICRONEEDLE-COATING SUBSTANCE, AND MICRONEEDLE ARRAY

Document Type and Number:

WIPO Patent Application WO/2017/135290

Kind Code:

A1

Abstract:

Provided is a composition for a coating liquid for microneedles which is optimal for when coating microneedles with a drug. This coating liquid for microneedles is an aqueous solution which has, as essential components of a base thereof, a water-soluble polysaccharide, a monosaccharide and/or a disaccharide, and a surfactant, and is characterized in that: the proportion of the water-soluble polysaccharide in the base is 2-60 mass%; and the hardness of a coating substance after drying is at least 10 N. A water-soluble polyhydric alcohol may also be included. It is preferable that, in the base, the proportion of the monosaccharide and/or the disaccharide be 30-95 mass%, the proportion of the surfactant be 0.05-5 mass%, and the proportion of the water-soluble polyhydric alcohol be not more than 10 mass%. Hydroxypropyl cellulose, hyaluronic acid, or carboxymethyl cellulose is preferable as the water-soluble polysaccharide.

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Inventors:

QUAN YING-SHU (JP)
SAITO MIO (JP)
KITAOKA SHOUTA (JP)
KAMIYAMA FUMIO (JP)

Application Number:

PCT/JP2017/003565

Publication Date:

August 10, 2017

Filing Date:

February 01, 2017

Export Citation:

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Assignee:

COSMED PHARMACEUTICAL CO LTD (JP)

International Classes:

A61K47/26; A61K9/08; A61K9/70; A61K47/10; A61K47/34; A61K47/36; A61M37/00

Domestic Patent References:

WO2011148994A1	2011-12-01
WO2012115207A1	2012-08-30
WO2008139648A1	2008-11-20

Foreign References:

JP2008510520A	2008-04-10
JP2011224308A	2011-11-10

Other References: