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Title:
COGNITIVE DISORDER PREVENTION AND THERAPY
Document Type and Number:
WIPO Patent Application WO/2021/140103
Kind Code:
A1
Abstract:
The present invention relates to the prevention or treatment of cognitive disorders, in which subjects, in particular subjects at risk of developing a cognitive disorder are treated with dopamine D4 (and serotonin 5-HT2A) receptor antagonists, reverse agonists, or partial agonists.

Inventors:
BUNTINX ERIK (BE)
Application Number:
PCT/EP2021/050091
Publication Date:
July 15, 2021
Filing Date:
January 05, 2021
Export Citation:
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Assignee:
ANIMA (BE)
International Classes:
A61K31/16; A61P25/28
Foreign References:
EP1541197A12005-06-15
US20050119249A12005-06-02
CA2461248A12005-06-02
Other References:
YOUNGSOON YANG ET AL: "Improvement of Cognitive Function after Computer-Based Cognitive Training in Early Stage of Alzheimer's Dementia", DEMENTIA AND NEUROCOGNITIVE DISORDERS, vol. 16, no. 1, 1 January 2017 (2017-01-01), pages 7, XP055722856, ISSN: 1738-1495, DOI: 10.12779/dnd.2017.16.1.7
JENSSEN ET AL., ALZHEIMERS DEMENT, vol. 10, no. 6, 2014, pages 844 - 52
NETNITRINI, DEMENT NEUROPSYCHOL, vol. 10, no. 3, 2016, pages 170 - 77
FOLSTEIN MFFOLSTEIN SEMCHUGH PR: "Mini-mental state'': a practical method for grading the cognitive state of patients for the clinician", J PSYCHIATR RES, vol. 12, no. 3, 1975, pages 189 - 98
MOLLOYSTANDISH: "A guide to the standardized Mini-Mental State Examination", PSYCHOGERIATR, vol. 9, 1997, pages 87 - 94
O-BRYANT ET AL.: "Detecting dementia with the mini-mental state examination (MMSE) in highly educated individuals", ARCH NEUROL, vol. 65, no. 7, 2008, pages 963 - 967
RUSH ET AL., PSYCHIATRY RESEARCH, vol. 18, 1986, pages 65 - 87
RUSH ET AL., PSYCHOLOGICAL MEDICINE, vol. 26, 1996, pages 477 - 486
"Pharmaceutics and Pharmacy Practice", 1982, J.B. LIPPINCOTT COMPANY, pages: 238 - 250
"ASHP Handbook on Injectable Drugs", 1986, TOISSEL, pages: 622 - 630
Attorney, Agent or Firm:
DE CLERCQ & PARTNERS et al. (BE)
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