COMBINATION THERAPY FOR TREATING ABNORMAL CELL GROWTH

Title:

COMBINATION THERAPY FOR TREATING ABNORMAL CELL GROWTH

Document Type and Number:

WIPO Patent Application WO/2023/108110

Kind Code:

A3

Abstract:

The present invention relates, in part, to methods, compounds, and compositions of an autophagy pathway inhibitor in combination with a dual RAF/MEK inhibitor, for treating abnormal cell growth (e.g., cancer).

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Inventors:

CHOWDHURY SANJIB (US)
PACHTER JONATHAN A (US)
COMA SILVIA (US)
BRYANT KIRSTEN LEIGH (US)
DER CHANNING JOSEPH (US)
CHANG WEN-HSUAN (US)
DELIBERTY JONATHAN MICHAEL (US)

Application Number:

PCT/US2022/081248

Publication Date:

September 14, 2023

Filing Date:

December 09, 2022

Export Citation:

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Assignee:

VERASTEM INC (US)
UNIV NORTH CAROLINA CHAPEL HILL (US)

International Classes:

A61K31/506; A61K45/06; A61P35/00

Domestic Patent References:

WO2021154929A1

2021-08-05

Foreign References:

US20200368238A1	2020-11-26
US20140113930A1	2014-04-24
US20100004233A1	2010-01-07
US20210154198A1	2021-05-27
US20170020884A1	2017-01-26

Attorney, Agent or Firm:

CHOI, Boyeon (US)

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