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Title:
COMBINATION USE OF CHOLESTANOL DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2010/100686
Kind Code:
A1
Abstract:
Disclosed is a cancer chemotherapeutic agent having reduced adverse side effects and excellent efficacy. The cancer chemotherapeutic agent comprises a combination of a cholestanol derivative represented by general formula (1) [wherein G represents GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal- or GlcNAc-] or a cyclodextrin inclusion compound thereof and an anti-cancer agent.

Inventors:
YAZAWA SHIN (JP)
NISHIMURA TOYO (JP)
ASAO TAKAYUKI (JP)
Application Number:
PCT/JP2009/004353
Publication Date:
September 10, 2010
Filing Date:
September 03, 2009
Export Citation:
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Assignee:
OTSUKA PHARMA CO LTD (JP)
UNIV GUNMA NAT UNIV CORP (JP)
YAZAWA SHIN (JP)
NISHIMURA TOYO (JP)
ASAO TAKAYUKI (JP)
International Classes:
A61K31/704; A61K31/282; A61K31/337; A61K31/519; A61K31/7072; A61K33/243; A61K45/00; A61P35/00; A61P43/00; C07J9/00
Domestic Patent References:
WO2005007172A12005-01-27
WO2007026869A12007-03-08
WO2005118071A22005-12-15
WO2005007172A12005-01-27
WO2007026869A12007-03-08
Foreign References:
JP2000191685A2000-07-11
JPH1160592A1999-03-02
JP2000191685A2000-07-11
JPH1160592A1999-03-02
JPS5782310A1982-05-22
JPS6012127A1985-01-22
JPS6058915A1985-04-05
JPH01117824A1989-05-10
JPH01167218A1989-06-30
JPH0429925A1992-01-31
JPH0987168A1997-03-31
Other References:
METHODS OF BIOCHEMICAL ANALYSIS, vol. 33, 1988, pages 337
See also references of EP 2404608A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
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