Title:
COMBINATIONS OF STEROL ABSORPTION INHIBITOR(S) WITH CARDIOVASCULAR AGENT(S) FOR THE TREATMENT OF VASCULAR CONDITIONS
Document Type and Number:
WIPO Patent Application WO2002058731
Kind Code:
A3
Abstract:
The present invention provides compositions, therapeutic combinations and methods including: (a) at least one sterol absorption inhibitor and (b) at least one cardiovascular agent different from the sterol absorption inhibitor, which can be useful for treating vascular conditions, obesity, diabetes and lowering plasma levels of sterols.
Inventors:
KOSOGLOU TEDDY
RESS RUDYARD JOSEPH
STRONY JOHN
VELTRI ENRICO P
HAUER WILLIAM
RESS RUDYARD JOSEPH
STRONY JOHN
VELTRI ENRICO P
HAUER WILLIAM
Application Number:
PCT/US2002/001196
Publication Date:
November 20, 2003
Filing Date:
January 25, 2002
Export Citation:
Assignee:
SCHERING CORP (US)
International Classes:
A61K45/06; A61K31/337; A61K31/397; A61K31/44; A61K31/455; A61K31/60; A61K31/655; A61K31/7052; A61K31/74; A61K38/55; A61P3/04; A61P3/06; A61P3/10; A61P7/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P43/00; C07D205/08; (IPC1-7): A61K45/06; A61P9/00; A61K31/395
Domestic Patent References:
| WO1995035277A1 | 1995-12-28 | |||
| WO2000038725A1 | 2000-07-06 |
Other References:
THOMPSON G. R. ET AL: "Novel lipid regulating drugs", EXPERT OPINION ON INVESTIGATIONAL DRUGS, vol. 9, no. 11, November 2000 (2000-11-01), pages 2619 - 2627, XP008011782
KOSOGLOU T. ET AL: "Coadministration of ezetimibe and fenofibrate leads to favorable effects on Apo CII and LDL subfractions", ATHEROSCLEROSIS, vol. 2, no. Suppl, 2001, pages 89, XP001132089
KOSOGLOU T. ET AL: "Coadministration of ezetimibe and fenofibrate leads to favorable effects on Apo CII and LDL subfractions", ATHEROSCLEROSIS, vol. 2, no. Suppl, 2001, pages 89, XP001132089
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