Title:
COMBINED FORMULATION KIT FOR ANALYZING PHENOTYPE AND FUNCTION OF CD1C+ DENDRITIC CELL SUBSET AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/036105
Kind Code:
A1
Abstract:
Disclosed are a combined formulation kit for analyzing the phenotype and function of a CD1c + dendritic cell subset and the use thereof, wherein the detection objects of the kit include CD1c, CD40, IL-6 and IL-10. The kit can be used to efficiently and quickly identify the phenotype of a CD1c + dendritic cell subset in peripheral blood and analyze the function thereof, thereby ensuring accuracy and reducing the economic cost produced by detecting a large number of surface antigen molecules, and the detection method is also simple to implement.
Inventors:
ZHOU FANG (CN)
CHEN XIAOPING (CN)
QIN LI (CN)
GU YANLI (CN)
XU WENLONG (CN)
LU YONG (CN)
CHANG XU (CN)
WEI GUOJIAN (CN)
RONG ZHIEN (CN)
CHEN XIAOPING (CN)
QIN LI (CN)
GU YANLI (CN)
XU WENLONG (CN)
LU YONG (CN)
CHANG XU (CN)
WEI GUOJIAN (CN)
RONG ZHIEN (CN)
Application Number:
PCT/CN2019/126389
Publication Date:
March 04, 2021
Filing Date:
December 18, 2019
Export Citation:
Assignee:
GUANGZHOU CAS LAMVAC BIOTECH CO LTD (CN)
International Classes:
G01N33/574; G01N33/533
Domestic Patent References:
| WO2017129981A1 | 2017-08-03 |
Foreign References:
| CN105911292A | 2016-08-31 | |||
| CN110389221A | 2019-10-29 | |||
| CN104955941A | 2015-09-30 | |||
| US20130225427A1 | 2013-08-29 |
Other References:
DILLON STEPHANIE M., ROGERS LISA M., HOWE RAWLEIGH, HOSTETLER LYDIA A., BUHRMAN JONATHAN, MCCARTER MARTIN D., WILSON CARA C.: "Human Intestinal Lamina Propria CD1c + Dendritic Cells Display an Activated Phenotype at Steady State and Produce IL-23 in Response to TLR7/8 Stimulation", THE JOURNAL OF IMMUNOLOGY, WILLIAMS & WILKINS CO., US, vol. 184, no. 12, 15 June 2010 (2010-06-15), US, pages 6612 - 6621, XP055786023, ISSN: 0022-1767, DOI: 10.4049/jimmunol.1000041
LU YONG, XU WENLONG, GU YANLI, CHANG XU, WEI GUOJIAN, RONG ZHIEN, QIN LI, CHEN XIAOPING, ZHOU FANG: "Non-small Cell Lung Cancer Cells Modulate the Development of Human CD1c+ Conventional Dendritic Cell Subsets Mediated by CD103 and CD205", FRONTIERS IN IMMUNOLOGY, vol. 10, 1 January 2019 (2019-01-01), pages 2829, XP055786019, DOI: 10.3389/fimmu.2019.02829
LU YONG, XU WENLONG, GU YANLI, CHANG XU, WEI GUOJIAN, RONG ZHIEN, QIN LI, CHEN XIAOPING, ZHOU FANG: "Non-small Cell Lung Cancer Cells Modulate the Development of Human CD1c+ Conventional Dendritic Cell Subsets Mediated by CD103 and CD205", FRONTIERS IN IMMUNOLOGY, vol. 10, 1 January 2019 (2019-01-01), pages 2829, XP055786019, DOI: 10.3389/fimmu.2019.02829
Attorney, Agent or Firm:
BEYOND ATTORNEYS AT LAW (CN)
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