Title:
COMPOSITE MATERIAL WITH RAPID BLOOD COAGULATION EFFECT AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2023/065541
Kind Code:
A1
Abstract:
Disclosed in the present invention are a composite material with a rapid blood coagulation effect and a preparation method therefor, which belong to the technical field of biomedicine. The composite material with the rapid blood coagulation effect comprises the following raw materials in parts by mass: 8-20 parts of chitosan, 7-14 parts of salicylaldehyde, 8-16 parts of 2-aminoisonicotinic acid, 1.5-3.5 parts of ferrous sulfate, 3-5 parts of dopa and 10-15 parts of disodium hydrogen phosphate. The composite material with the rapid blood coagulation effect prepared by means of the present invention has good product stability, high biological safety, a significant effect on blood coagulation and a simple process, and is convenient for industrial production.
Inventors:
HU ZHANG (CN)
ZHANG ZHAOYU (CN)
LU SITONG (CN)
HUANG DEJIAN (CN)
YU JIAYIN (CN)
CHENG YU (CN)
LIAO MINGNENG (CN)
ZHANG ZHAOYU (CN)
LU SITONG (CN)
HUANG DEJIAN (CN)
YU JIAYIN (CN)
CHENG YU (CN)
LIAO MINGNENG (CN)
Application Number:
PCT/CN2022/070418
Publication Date:
April 27, 2023
Filing Date:
January 06, 2022
Export Citation:
Assignee:
UNIV GUANGDONG OCEAN (CN)
International Classes:
A61L15/18; A61L15/28; A61L15/20; A61L15/42; A61L15/44; A61L15/46; C08B37/08
Foreign References:
| CN113769150A | 2021-12-10 | |||
| CN111870731A | 2020-11-03 | |||
| CN103145738A | 2013-06-12 |
Other References:
GUAN JING, HE QIN, WANG XIAO HUI, HUANG SHU JIE, LI ZHI HONG, LIU CHANG JUN, LI FAN, SHU ZHAN: "Preparation and Blood Coagulation Property of Ortho Hydroxytoluene Chitosan", MATERIALS SCIENCE FORUM, TRANS TECH PUBLICATIONS LTD, vol. 893, 1 January 2017 (2017-01-01), pages 62 - 68, XP093057705, DOI: 10.4028/www.scientific.net/MSF.893.62
JIANG YUEXIA, ET AL.: "Basis Properties and safety Assessment of DOPA-Chitosan Hemostatic Sponge", JOURNAL OF QIQIHAR MEDICAL COLLEGE, XX, XX, vol. 34, no. 16, 31 December 2013 (2013-12-31), xx , pages 2341 - 2342, XP093057704, ISSN: 1002-1256
JIANG YUEXIA, ET AL.: "Basis Properties and safety Assessment of DOPA-Chitosan Hemostatic Sponge", JOURNAL OF QIQIHAR MEDICAL COLLEGE, XX, XX, vol. 34, no. 16, 31 December 2013 (2013-12-31), xx , pages 2341 - 2342, XP093057704, ISSN: 1002-1256
Attorney, Agent or Firm:
BEIJING DONGFANGSHENGFAN IP AGENCY CO., LTD. (CN)
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