COMPOSITION FOR ALLEVIATING PREMENSTRUAL SYNDROME, CONTAINING MIXED LACTOBACILLUS STRAINS AS ACTIVE INGREDIENT

Title:

COMPOSITION FOR ALLEVIATING PREMENSTRUAL SYNDROME, CONTAINING MIXED LACTOBACILLUS STRAINS AS ACTIVE INGREDIENT

Document Type and Number:

WIPO Patent Application WO/2023/038350

Kind Code:

A1

Abstract:

The purpose of the present application is to provide a composition for alleviating premenstrual syndrome, containing, as an active ingredient, mixed strains of a Lactobacillus gasseri LM1065 strain (KCCM13018P) and a Lactobacillus reuteri LM1071 strain (KCCM12650P), or any one from among a culture product, a lysate, and an extract of the mixed strains. Mixed strains of a Lactobacillus gasseri LM1065 strain (KCCM13018P) and a Lactobacillus reuteri LM1071 strain (KCCM12650P), according to one implementation of the present application, reduce the production of blood NO and the expression of IL-6, iNOS and COX-2 genes and increase the production rate of blood prostaglandin E1/prostaglandin E2 and the levels of blood GLA and DGLA, so that premenstrual syndrome can be alleviated, and thus the mixed strains can be applied to food compositions, health functional food compositions, pharmaceutical compositions and the like.

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Inventors:

SOHN MINN (KR)
KIM TAE RAHK (KR)
BAE WON YOUNG (KR)

Application Number:

PCT/KR2022/012862

Publication Date:

March 16, 2023

Filing Date:

August 29, 2022

Export Citation:

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Assignee:

LACTOMASON CO LTD (KR)

International Classes:

A61K35/747; A23L33/135; A61P15/02

Domestic Patent References:

WO2021015104A1	2021-01-28
WO2019235451A1	2019-12-12

Foreign References:

KR102268128B1	2021-06-22
US20190307817A1	2019-10-10

Other References:

SAWADA DAISUKE; KUWANO YUKI; TANAKA HIROKI; HARA SUSUMU; UCHIYAMA YOSHIHIDE; SUGAWARA TOMONORI; FUJIWARA SHIGERU; ROKUTAN KAZUHITO: "Daily intake ofLactobacillus gasseriCP2305 relieves fatigue and stress-related symptoms in male university Ekiden runners: A double-blind, randomized, and placebo-controlled clinical trial", JOURNAL OF FUNCTIONAL FOODS, ELSEVIER BV, NL, vol. 57, 1 January 1900 (1900-01-01), NL , pages 465 - 476, XP085687639, ISSN: 1756-4646, DOI: 10.1016/j.jff.2019.04.022

Attorney, Agent or Firm:

MAPS INTELLECTUAL PROPERTY LAW FIRM (KR)

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