Title:
COMPOSITION FOR COMPETITIVE INHIBITION OF OREXIN RECEPTORS
Document Type and Number:
WIPO Patent Application WO/2020/158415
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a novel composition for competitive inhibition of orexin receptors which is able to inhibit orexin from binding to receptors thereof; and a method for inhibiting orexin from binding to receptors thereof. The present invention relates to a composition for competitive inhibition of orexin receptors which contains pyrroloquinoline quinone or a salt thereof as an active ingredient.
Inventors:
ITOGA SHOTA (JP)
WATANABE HIROSHI (JP)
TAKANO JIRO (JP)
WATANABE HIROSHI (JP)
TAKANO JIRO (JP)
Application Number:
PCT/JP2020/001288
Publication Date:
August 06, 2020
Filing Date:
January 16, 2020
Export Citation:
Assignee:
SUNTORY HOLDINGS LTD (JP)
International Classes:
A61P25/20; A23L29/00; A23L33/10; A61K31/4745; A61P25/28; A61P43/00
Domestic Patent References:
| WO2006025247A1 | 2006-03-09 | |||
| WO2007119588A1 | 2007-10-25 | |||
| WO2016084866A1 | 2016-06-02 |
Foreign References:
| JP2017114844A | 2017-06-29 | |||
| JP2012019739A | 2012-02-02 | |||
| JP2018534338A | 2018-11-22 | |||
| JP2013515033A | 2013-05-02 | |||
| JP2018135349A | 2018-08-30 |
Other References:
ROECKER, A.J. ET AL.: "Orexin receptor antagonists: new therapeutic agents for the treatment of insomnia", JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, no. 2, 28 January 2016 (2016-01-28), pages 504 - 530, XP055726104
SLEEP, vol. 36, no. 2, 1 February 2013 (2013-02-01), pages 259 - 267
ENDOCRINOLOGY, vol. 157, no. 11, November 2016 (2016-11-01), pages 4146 - 4157
SCIENCE, vol. 326, no. 5955, 13 November 2009 (2009-11-13), pages 1005 - 1007
See also references of EP 3919125A4
SLEEP, vol. 36, no. 2, 1 February 2013 (2013-02-01), pages 259 - 267
ENDOCRINOLOGY, vol. 157, no. 11, November 2016 (2016-11-01), pages 4146 - 4157
SCIENCE, vol. 326, no. 5955, 13 November 2009 (2009-11-13), pages 1005 - 1007
See also references of EP 3919125A4
Attorney, Agent or Firm:
YASUTOMI & ASSOCIATES (JP)
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