Title:
COMPOSITION COMPRISING AT LEAST AN ALKANOLAMIDE FOR INHIBITING LANGERHANS CELL MIGRATION, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2003055462
Kind Code:
A3
Abstract:
The invention concerns a composition containing at least an alkanolamide, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an oxazolin, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular its use for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such a composition on the skin and/or mucosa.
Inventors:
MSIKA PHILIPPE (FR)
PICCARDI NATHALIE (FR)
PICCIRILLI ANTOINE (FR)
PICCARDI NATHALIE (FR)
PICCIRILLI ANTOINE (FR)
Application Number:
PCT/FR2002/004582
Publication Date:
January 22, 2004
Filing Date:
December 27, 2002
Export Citation:
Assignee:
EXPANSCIENCE LAB (FR)
MSIKA PHILIPPE (FR)
PICCARDI NATHALIE (FR)
PICCIRILLI ANTOINE (FR)
MSIKA PHILIPPE (FR)
PICCARDI NATHALIE (FR)
PICCIRILLI ANTOINE (FR)
International Classes:
A61K8/30; A61K8/00; A61K8/40; A61K8/42; A61K8/49; A61K8/68; A61K8/97; A61K8/98; A61K31/164; A61K31/421; A61K38/55; A61P5/00; A61P17/00; A61P17/06; A61P29/00; A61P37/06; A61P37/08; A61P43/00; A61Q19/00; A61Q19/08; (IPC1-7): A61K7/48
Domestic Patent References:
| WO1999029293A1 | 1999-06-17 | |||
| WO1995029151A1 | 1995-11-02 | |||
| WO2002072082A1 | 2002-09-19 | |||
| WO1999041266A1 | 1999-08-19 |
Foreign References:
| US6001375A | 1999-12-14 | |||
| DE19841794A1 | 2000-03-16 | |||
| US6159485A | 2000-12-12 |
Other References:
E. BERARDESCA ET AL.: "Evaluation of efficacy of a skin lipid mixture in patients with irritant contact dermatitis, allergic contact dermatitis or atopic dermatitis: a multicenter study.", CONTACT DERMATITIS, vol. 45, no. 5, 2001, dk, pages 280 - 285, XP001128103
T. SAKAI ET AL.: "Ceramide derivatives as therapeutic agents", EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 8, no. 12, 1998, pages 1673 - 1682, XP001127407
G. HALLIDAY ET AL.: "Protein kinase C transduces the signal for Langerhans' cell migration from the epidermis.", IMMUNOLOGY, vol. 79, 1993, pages 621 - 626, XP001011467
R. ANORA ET AL: "Stimulation in vitro of galactocerebroside galactosidase by N-decanoyl 2-amino-2-methylpropanol", LIPIDS, vol. 7, no. 1, 1972, pages 56 - 59, XP000645675
T. SAKAI ET AL.: "Ceramide derivatives as therapeutic agents", EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 8, no. 12, 1998, pages 1673 - 1682, XP001127407
G. HALLIDAY ET AL.: "Protein kinase C transduces the signal for Langerhans' cell migration from the epidermis.", IMMUNOLOGY, vol. 79, 1993, pages 621 - 626, XP001011467
R. ANORA ET AL: "Stimulation in vitro of galactocerebroside galactosidase by N-decanoyl 2-amino-2-methylpropanol", LIPIDS, vol. 7, no. 1, 1972, pages 56 - 59, XP000645675
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