Title:
COMPOSITION COMPRISING COLLAGENASE, CALCIUM, HISTIDINE, AND GLYCINE, AND METHOD FOR STABILIZING COLLAGENASE
Document Type and Number:
WIPO Patent Application WO/2023/172070
Kind Code:
A1
Abstract:
The present invention provides a composition comprising collagenase as an enzyme; calcium, histidine, and glycine as coenzymes, and a method for stabilizing enzymes, the method comprising the preparation of the composition by adding histidine and glycine to collagenase. According to the present invention, the enzyme composition and method for stabilizing enzymes can minimize or inhibit the agglutination of enzymes, maintain the concentration of freeze-dried enzymes even during long-term storage, and provide a formulation that has excellent rehydration time and hygroscopicity when restored to a liquid state, as well as superior enzyme activity.
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Inventors:
CHOI CHI MIN (KR)
RYU CHOONG SUN (KR)
KIM SUNG HEE (KR)
RYU CHOONG SUN (KR)
KIM SUNG HEE (KR)
Application Number:
PCT/KR2023/003188
Publication Date:
September 14, 2023
Filing Date:
March 08, 2023
Export Citation:
Assignee:
CONNEXT CO LTD (KR)
International Classes:
C12N9/96; C12N9/64
Domestic Patent References:
| WO2008084237A2 | 2008-07-17 | |||
| WO1994024272A1 | 1994-10-27 |
Foreign References:
| KR20210113271A | 2021-09-15 | |||
| KR20190136030A | 2019-12-09 | |||
| KR20000060771A | 2000-10-16 |
Attorney, Agent or Firm:
TAEDONG PATENT & LAW FIRM (KR)
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