Title:
COMPOSITION COMPRISING TAT PEPTIDE VARIANT AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING METABOLIC DISEASES
Document Type and Number:
WIPO Patent Application WO/2023/038462
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition and a functional food composition, each comprising a TAT peptide variant as an active ingredient for preventing or treating metabolic diseases, wherein the TAT peptide variant has a certain length of internal residues replaced by aliphatic amino carboxylic acid or polyethylene glycol. Retaining the fat reduction effect of the natural TAT peptide and having remarkably increased water solubility and yield, the composition of the present invention is easier to produce and excellently biocompatible and can be advantageously used as a composition for treating metabolic diseases.
Inventors:
HUR MAN-WOOK (KR)
PARK SUN-YOUNG (KR)
PARK SUJIN (KR)
SONG JI-YANG (KR)
CHOI SEOHYUN (KR)
YOON YOUNGSO (KR)
PARK SUN-YOUNG (KR)
PARK SUJIN (KR)
SONG JI-YANG (KR)
CHOI SEOHYUN (KR)
YOON YOUNGSO (KR)
Application Number:
PCT/KR2022/013529
Publication Date:
March 16, 2023
Filing Date:
September 08, 2022
Export Citation:
Assignee:
UNIV YONSEI IACF (KR)
International Classes:
C07K7/08; A23L33/18; A61K38/00; A61P1/16; A61P3/04; A61P3/06; A61P3/10; C07K7/06; C07K14/005
Domestic Patent References:
| WO2015127862A1 | 2015-09-03 |
Foreign References:
| US9969780B1 | 2018-05-15 | |||
| US6083706A | 2000-07-04 | |||
| US7795017B2 | 2010-09-14 | |||
| JPH04300816A | 1992-10-23 |
Attorney, Agent or Firm:
PADO IP LAW PLLC (KR)
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