Title:
COMPOSITION CONTAINING CURCUMIN COMPOUND, AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2021/153485
Kind Code:
A1
Abstract:
Provided are: a novel amorphous curcumin compound powdery composition which is inexpensive, is improved in the bioabsorbability and bioavailability of curcumin, and has long-term stability; and a method for producing the powdery composition. The present invention relates to: a powdery composition which comprises an amorphous curcumin compound and a hydrophilic modified starch and has a Raman spectrum including one or more peaks at wavenumbers (expressed in ± 2 cm-1) of 1630, 1599, 1428 and 1243; and a method for producing the powdery composition.
Inventors:
ITOH MASASHI (JP)
NISHIMURA SATOSHI (JP)
OGAWA TATSUYA (JP)
HASHIMOTO TADASHI (JP)
NISHIMURA SATOSHI (JP)
OGAWA TATSUYA (JP)
HASHIMOTO TADASHI (JP)
Application Number:
PCT/JP2021/002393
Publication Date:
August 05, 2021
Filing Date:
January 25, 2021
Export Citation:
Assignee:
THERABIOPHARMA INC (JP)
International Classes:
A61K31/12; A23L33/105; A61K47/36; A61P3/06; A61P9/00; A61P25/28; A61P29/00; A61P35/00; A61P37/08; A61P39/06
Domestic Patent References:
| WO2018159853A1 | 2018-09-07 | |||
| WO2011129284A1 | 2011-10-20 | |||
| WO2014174475A1 | 2014-10-30 |
Other References:
ATHIRA GEETHA K., JYOTHI ALUMMOOTTIL N., VISHNU VIJAYAKUMAR R.: "Water Soluble Octenyl Succinylated Cassava Starch-Curcumin Nanoformulation With Enhanced Bioavailability and Anticancer Potential", STARCH/STARKE, WILEY-VCH VERLAG, WEINHEIM., DE, vol. 70, no. 7-8, 1 July 2018 (2018-07-01), DE, pages 1700178, XP055843600, ISSN: 0038-9056, DOI: 10.1002/star.201700178
LIU DONG: "Engineering nano-curcumin with enhanced solubility and in-vitro anti-cancer bioactivity", MASTER THESIS, THE STATE UNIVERSITY OF NEW JERSEY, NO PUBLISHER SUPPLIED, 1 October 2013 (2013-10-01), XP055843612, DOI: 10.7282/t3s75dcf
SANPHUI, P ET AL.: "Crurcumin-a biological wonder molecule: A crystal engineerring point of review", CRYST. GROWTH DES, PUBLICATION DATE(WEB, 25 July 2018 (2018-07-25)
PAWAR, Y. B. ET AL.: "Phase behaivior and oral bioavailability of amorphous Curcumin, Euro", J. OF PHARMACEUTICAL SCIENCES, vol. 47, 2012, pages 56 - 64
See also references of EP 4098255A4
LIU DONG: "Engineering nano-curcumin with enhanced solubility and in-vitro anti-cancer bioactivity", MASTER THESIS, THE STATE UNIVERSITY OF NEW JERSEY, NO PUBLISHER SUPPLIED, 1 October 2013 (2013-10-01), XP055843612, DOI: 10.7282/t3s75dcf
SANPHUI, P ET AL.: "Crurcumin-a biological wonder molecule: A crystal engineerring point of review", CRYST. GROWTH DES, PUBLICATION DATE(WEB, 25 July 2018 (2018-07-25)
PAWAR, Y. B. ET AL.: "Phase behaivior and oral bioavailability of amorphous Curcumin, Euro", J. OF PHARMACEUTICAL SCIENCES, vol. 47, 2012, pages 56 - 64
See also references of EP 4098255A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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