Title:
COMPOSITION CONTAINING POLYSULFIDE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2020/158894
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing: a composition that contains a polysulfide compound having improved stability or a pharmaceutically acceptable salt thereof; an agent for improving the stability of the polysulfide compound or of a pharmaceutically acceptable salt thereof; and a method for improving the stability of the polysulfide compound or of a pharmaceutically acceptable salt thereof. The present invention makes it possible to provide a composition that contains a polysulfide compound having improved stability or a pharmaceutically acceptable salt thereof by causing a polysulfide compound or a pharmaceutically acceptable salt thereof to coexist with one or more compounds selected from the group consisting of stabilizing agents and unsaturated hydrocarbon compounds.
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Inventors:
MATSUNO SHINYA (JP)
Application Number:
PCT/JP2020/003538
Publication Date:
August 06, 2020
Filing Date:
January 30, 2020
Export Citation:
Assignee:
KYOWA HAKKO BIO CO LTD (JP)
International Classes:
A61P27/04; A23L33/10; A61K9/06; A61K9/08; A61K9/14; A61K9/16; A61K9/20; A61K9/48; A61K9/70; A61K38/06; A61K47/06; A61K47/18; A61K47/46; A61P17/00; A61Q19/00; A61J1/00
Foreign References:
| JPH11346706A | 1999-12-21 | |||
| JPH1094379A | 1998-04-14 | |||
| JP2002255757A | 2002-09-11 | |||
| JP2014076010A | 2014-05-01 | |||
| JP2003210132A | 2003-07-29 |
Other References:
HAMID, HISYAM ABDUL ET AL.: "Polysulfide stabilization by tyrosine and hydroxyphenyl- containing derivatives that is important for a reactive sulfur metabolomics analysis", REDOX BIOLOGY, vol. 21, no. 101096, 2 January 2019 (2019-01-02), pages 1 - 7, XP055730041
EVERETT, STEVEN A. ET AL.: "Perthiyl Radicals, Trisulfide Radical Ions, and Sulfate Formation. A Combined Photolysis and Radiolysis Study on Redox Processes with Organic Di-and Trisulfides", J. PHYS. CHEM., vol. 96, 1992, pages 306 - 314, XP055730047
EVERETT, STEVEN A. ET AL.: "Perthiyl Radicals, Trisulfide Radical Ions, and Sulfate Formation. A Combined Photolysis and Radiolysis Study on Redox Processes with Organic Di-and Trisulfides", J. PHYS. CHEM., vol. 96, 1992, pages 306 - 314, XP055730047
Attorney, Agent or Firm:
EIKOH PATENT FIRM, P.C. (JP)
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