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Title:
COMPOSITION CONTAINING RHIZOMA GALANGAE EXTRACT AND CHRYSANTHEMUM EXTRACT AND HAVING URIC ACID REDUCING FUNCTION AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/223241
Kind Code:
A1
Abstract:
Disclosed are a composition containing a rhizoma galangae extract and a chrysanthemum extract and having a uric acid reducing function and an application thereof. The rhizoma galangae extract is made of dry rhizoma galangae and is obtained by the combination of an ultrasound-assisted ethanol extraction method and a macroporous resin separation and enrichment method, and diphenylheptane and flavone compounds in the rhizoma galangae are extracted effectively. The chrysanthemum extract is made of dry Bo chrysanthemum, Qi chrysanthemum and Jinsihuang chrysanthemum by means of an ethanol refluxing extraction method, and flavone substances in the chrysanthemums are extracted effectively. The composition contains more than 30% of diphenylheptane compounds an more than 7% of flavone compounds, and has a remarkable uric acid reducing activity, and the in-vitro xanthine oxidase inhibitory activity is higher than 75μmol of allopurinol equivalent weight/g. The composition can be applied to health-care foods or medicines for the prevention and adjuvant therapy of hyperuricemia.

Inventors:
LIN LIANZHU (CN)
PENG AN (CN)
ZHAO MOUMING (CN)
LIU XUEMEI (CN)
SU GUOWAN (CN)
Application Number:
PCT/CN2018/112824
Publication Date:
November 28, 2019
Filing Date:
October 30, 2018
Export Citation:
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Assignee:
UNIV SOUTH CHINA TECH (CN)
International Classes:
A61K36/9062; A23L33/105; A61K36/287; A61P19/06
Foreign References:
CN108404020A2018-08-17
Other References:
XUE XUE-MEI ET AL: "Effect of Total Flavonoids of Galangal in Lowering Uric Acid", HUNAN JOURNAL OF TRADITIONAL CHINESE MEDICINE, vol. 34, no. 2, 28 February 2018 (2018-02-28), pages 143 - 145, XP055656877, DOI: 10.16808/j.cnki. issn1003 -7705.2018.02.069
Attorney, Agent or Firm:
YOGO PATENT & TRADEMARK AGENCY LIMITED COMPANY (CN)
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