Title:
COMPOSITION FOR DIAGNOSING INSULIN RESISTANCE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/174575
Kind Code:
A1
Abstract:
Genes used as criteria in the present invention are highly related to insulin resistance. Specifically, the present invention relates to a method and a kit for diagnosing insulin resistance with a high accuracy on the basis of the expression level of the genes or for screening candidates for insulin resistance therapeutic agents.
Inventors:
JANG WON HEE (KR)
JUNG JUNG HYUN (KR)
JUNG JUNG HYUN (KR)
Application Number:
PCT/KR2018/003319
Publication Date:
September 27, 2018
Filing Date:
March 21, 2018
Export Citation:
Assignee:
UNIV DONGGUK IND ACAD COOP (KR)
International Classes:
C12Q1/6883; G01N33/68
Domestic Patent References:
| WO2012095313A1 | 2012-07-19 |
Foreign References:
| US20110003296A1 | 2011-01-06 | |||
| US20130210039A1 | 2013-08-15 |
Other References:
GO, YOUNGHOON: "Inhibition of pyruvate dehydrogenase kinase 2 protects against hepatic steatosis through modulation of TCA cycle anaplerosis and ketogenesis", DIABETES, vol. 65, no. 10, 2016, pages 2876 - 2887, XP055608705, ISSN: 0012-1797, DOI: 10.2337/db16-0223
MULLEN, EDEL: "Proteomic profiling of non-obese type 2 diabetic skeletal muscle", INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, vol. 25, no. 3, 2010, pages 445 - 458, XP055608708, ISSN: 1107-3756, DOI: 10.3892/ijmm_00000364
JUNG, JUNGHYUN: "Meta-and cross-species analyses of insulin resistance based on gene expression datasets in human white adipose tissues", SCIENTIFIC REPORTS, vol. 8, no. 3747, 27 February 2018 (2018-02-27), pages 1 - 13, XP055608716, DOI: 10.1038/s41598-017-18082-7
MULLEN, EDEL: "Proteomic profiling of non-obese type 2 diabetic skeletal muscle", INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, vol. 25, no. 3, 2010, pages 445 - 458, XP055608708, ISSN: 1107-3756, DOI: 10.3892/ijmm_00000364
JUNG, JUNGHYUN: "Meta-and cross-species analyses of insulin resistance based on gene expression datasets in human white adipose tissues", SCIENTIFIC REPORTS, vol. 8, no. 3747, 27 February 2018 (2018-02-27), pages 1 - 13, XP055608716, DOI: 10.1038/s41598-017-18082-7
Attorney, Agent or Firm:
DOOHO IP LAW FIRM (KR)
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