Title:
COMPOSITION FOR ENHANCING SIRT3 GENE EXPRESSION
Document Type and Number:
WIPO Patent Application WO/2023/228994
Kind Code:
A1
Abstract:
The present disclosure addresses the problem of providing at least a technology for enhancing the expression of SIRT3 genes. Said problem is solved by a composition for enhancing SIRT3 gene expression, the composition containing urolithin M3 as an active ingredient.
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Inventors:
OOE KENICHI (JP)
UKAWA YUICHI (JP)
NAKAJIMA TAKANORI (JP)
KATAKURA YOSHINORI (JP)
UKAWA YUICHI (JP)
NAKAJIMA TAKANORI (JP)
KATAKURA YOSHINORI (JP)
Application Number:
PCT/JP2023/019433
Publication Date:
November 30, 2023
Filing Date:
May 25, 2023
Export Citation:
Assignee:
DAICEL CORP (JP)
UNIV KYUSHU NAT UNIV CORP (JP)
UNIV KYUSHU NAT UNIV CORP (JP)
International Classes:
A61K31/366; A23L33/10; A61K8/49; A61P17/16; A61P17/18; A61P25/28; A61P27/16; A61P39/06; A61P43/00; A61Q19/08; C12N15/12; C12Q1/6897
Domestic Patent References:
| WO2022162471A1 | 2022-08-04 | |||
| WO2022114152A1 | 2022-06-02 |
Foreign References:
| JP2017007951A | 2017-01-12 | |||
| JP2014501764A | 2014-01-23 | |||
| JP2017031108A | 2017-02-09 | |||
| JP2017019725A | 2017-01-26 |
Other References:
ISHIMOTO HIDEKAZU, TAI AKIHIRO, YOSHIMURA MORIO, AMAKURA YOSHIAKI, YOSHIDA TAKASHI, HATANO TSUTOMU, ITO HIDEYUKI: "Antioxidative Properties of Functional Polyphenols and Their Metabolites Assessed by an ORAC Assay", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, JP, vol. 76, no. 2, 23 February 2012 (2012-02-23), JP , pages 395 - 399, XP093111705, ISSN: 0916-8451, DOI: 10.1271/bbb.110717
LIU WENJIE, YAN FANG, XU ZHONGYI, CHEN QINYI, REN JIE, WANG QIANQIAN, CHEN LI, YING JIAYI, LIU ZIQI, ZHAO JUEMIN, QIU JU, ZHANG CH: "Urolithin A protects human dermal fibroblasts from UVA-induced photoaging through NRF2 activation and mitophagy", JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B: BIOLOGY, ELSEVIER SCIENCE S.A., BASEL., CH, vol. 232, 1 July 2022 (2022-07-01), CH , pages 112462, XP093111707, ISSN: 1011-1344, DOI: 10.1016/j.jphotobiol.2022.112462
WU DAN, JI HAIZHE, DU WENJUAN, REN LINA, QIAN GENG: "Mitophagy alleviates ischemia/reperfusion-induced microvascular damage through improving mitochondrial quality control", BIOENGINEERED, LANDES BIOSCIENCE, US, vol. 13, no. 2, 1 February 2022 (2022-02-01), US , pages 3596 - 3607, XP093111710, ISSN: 2165-5979, DOI: 10.1080/21655979.2022.2027065
LIU WENJIE, YAN FANG, XU ZHONGYI, CHEN QINYI, REN JIE, WANG QIANQIAN, CHEN LI, YING JIAYI, LIU ZIQI, ZHAO JUEMIN, QIU JU, ZHANG CH: "Urolithin A protects human dermal fibroblasts from UVA-induced photoaging through NRF2 activation and mitophagy", JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B: BIOLOGY, ELSEVIER SCIENCE S.A., BASEL., CH, vol. 232, 1 July 2022 (2022-07-01), CH , pages 112462, XP093111707, ISSN: 1011-1344, DOI: 10.1016/j.jphotobiol.2022.112462
WU DAN, JI HAIZHE, DU WENJUAN, REN LINA, QIAN GENG: "Mitophagy alleviates ischemia/reperfusion-induced microvascular damage through improving mitochondrial quality control", BIOENGINEERED, LANDES BIOSCIENCE, US, vol. 13, no. 2, 1 February 2022 (2022-02-01), US , pages 3596 - 3607, XP093111710, ISSN: 2165-5979, DOI: 10.1080/21655979.2022.2027065
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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