Title:
COMPOSITION, HYDROGEL, AND POLYMER, AND USE OF HYDROGEL
Document Type and Number:
WIPO Patent Application WO/2021/149785
Kind Code:
A1
Abstract:
To provide a polymer that can obtain excellent cell culture efficiency when used as an extracellular matrix material despite being an artificially synthesized polymer. A polymer that has a group having a peptide skeleton that includes an RGD sequence, and at least one group selected from groups having a thiol group and groups having an ethylenic unsaturated double bond.
Inventors:
YAMADA SHUHEI (JP)
ARAI TAKAYUKI (JP)
KUBO HIROTO (JP)
XU YINGJIA (JP)
HATA MARINA (JP)
ARAI TAKAYUKI (JP)
KUBO HIROTO (JP)
XU YINGJIA (JP)
HATA MARINA (JP)
Application Number:
PCT/JP2021/002127
Publication Date:
July 29, 2021
Filing Date:
January 22, 2021
Export Citation:
Assignee:
JSR CORP (JP)
International Classes:
C08G69/48; C08J3/075; C08L77/04; C12N5/071
Foreign References:
| JP2004010692A | 2004-01-15 |
Other References:
JURIGA DÁVID, NAGY KRISZTINA, JEDLOVSZKY-HAJDÚ ANGÉLA, PERCZEL-KOVÁCH KATALIN, CHEN YONG MEI, VARGA GÁBOR, ZRÍNYI MIKLÓS: "Biodegradation and Osteosarcoma Cell Cultivation on Poly(aspartic acid) Based Hydrogels", ACS APPL. MATER. INTERFACES, vol. 8, no. 36, 2016, pages 23463 - 23476, XP055843511
STUDENOVSKÁ HANA, VODIČKA PETR, PROKS VLADIMÍR, HLUČILOVÁ JANA, MOTLÍK JAN, RYPÁČEK FRANTIŠEK: "Synthetic poly(amino acid) hydrogels with incorporated cell-adhesion peptides for tissue engineering", J. TISSUE ENG. REGEN. MED., vol. 4, 2010, pages 454 - 463, XP055843519
LIU BO, LEWIS ANDREW K., SHEN WEI: "Physical Hydrogels Photo-Cross-Linked from Self-Assembled Macromers for Potential Use in Tissue Engineering", BIOMACROMOLECULES, vol. 10, no. 12, 2009, pages 3182 - 3187, XP055843531
LANEY M WEBER ET AL.: "The effects of cell -matrix interactions on encapsulated beta- cell function within hydrogels functionalized with matrix- derived adhesive peptides", BIOMATERIALS, vol. 28, 2007, pages 3004 - 3011, XP022039738, DOI: 10.1016/j.biomaterials.2007.03.005
CHA CHAENYUNG, JEONG JAE HYUN, TANG XIN, ZILL ANDREW T., PRAKASH Y. S., ZIMMERMAN STEVEN C., SAIF TAHER A., KONG HYUNJOON: "Top-down Synthesis of Versatile Polyaspartamide Linkers for Single-Step Protein Conjugation to Materials", BIOCONJUG. CHEM., vol. 22, 2011, pages 2377 - 2382, XP055843533
ADELNIA HOSSEIN, BLAKEY IDRISS, LITTLE PETER J., TA HANG T.: "Hydrogels Based on Poly(aspartic acid): Synthesis and Applications", FRONTIERS IN CHEMISTRY, vol. 7, 2019, pages 1 - 14, XP055843539
STUDENOVSKÁ HANA, VODIČKA PETR, PROKS VLADIMÍR, HLUČILOVÁ JANA, MOTLÍK JAN, RYPÁČEK FRANTIŠEK: "Synthetic poly(amino acid) hydrogels with incorporated cell-adhesion peptides for tissue engineering", J. TISSUE ENG. REGEN. MED., vol. 4, 2010, pages 454 - 463, XP055843519
LIU BO, LEWIS ANDREW K., SHEN WEI: "Physical Hydrogels Photo-Cross-Linked from Self-Assembled Macromers for Potential Use in Tissue Engineering", BIOMACROMOLECULES, vol. 10, no. 12, 2009, pages 3182 - 3187, XP055843531
LANEY M WEBER ET AL.: "The effects of cell -matrix interactions on encapsulated beta- cell function within hydrogels functionalized with matrix- derived adhesive peptides", BIOMATERIALS, vol. 28, 2007, pages 3004 - 3011, XP022039738, DOI: 10.1016/j.biomaterials.2007.03.005
CHA CHAENYUNG, JEONG JAE HYUN, TANG XIN, ZILL ANDREW T., PRAKASH Y. S., ZIMMERMAN STEVEN C., SAIF TAHER A., KONG HYUNJOON: "Top-down Synthesis of Versatile Polyaspartamide Linkers for Single-Step Protein Conjugation to Materials", BIOCONJUG. CHEM., vol. 22, 2011, pages 2377 - 2382, XP055843533
ADELNIA HOSSEIN, BLAKEY IDRISS, LITTLE PETER J., TA HANG T.: "Hydrogels Based on Poly(aspartic acid): Synthesis and Applications", FRONTIERS IN CHEMISTRY, vol. 7, 2019, pages 1 - 14, XP055843539
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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