Title:
COMPOSITION FOR IMMUNE ACTIVATION
Document Type and Number:
WIPO Patent Application WO/2006/087913
Kind Code:
A1
Abstract:
The invention relates to a composition for immune activation which comprises bacterial cells of bifidobacteria belonging to Bifidobacterium bifidum with an inducing ability of secretory substance production and a high inducing ability of IgA production, such as Bifidobacterium bifidum OLB6377 strain or Bifidobacterium bifidum OLB 6378 strain, or a substance obtained by treating the bacterial cells alone or in combination of a plurality of them and is useful for promoting production of IgA and a sectetory substance in a mucosal tissue.
Inventors:
MORO ITARU (JP)
IWASE TAKASHI (JP)
OCHIAI KUNIYASU (JP)
YAJIMA MASAKO (JP)
TERAHARA MASAKI (JP)
NAKAMURA YOSHITAKA (JP)
TOTSUKA MAMORU (JP)
YAMADA KIYOSHI (JP)
IWASE TAKASHI (JP)
OCHIAI KUNIYASU (JP)
YAJIMA MASAKO (JP)
TERAHARA MASAKI (JP)
NAKAMURA YOSHITAKA (JP)
TOTSUKA MAMORU (JP)
YAMADA KIYOSHI (JP)
Application Number:
PCT/JP2006/301661
Publication Date:
August 24, 2006
Filing Date:
February 01, 2006
Export Citation:
Assignee:
MEIJI DAIRIES CORP (JP)
MORO ITARU (JP)
IWASE TAKASHI (JP)
OCHIAI KUNIYASU (JP)
YAJIMA MASAKO (JP)
TERAHARA MASAKI (JP)
NAKAMURA YOSHITAKA (JP)
TOTSUKA MAMORU (JP)
YAMADA KIYOSHI (JP)
MORO ITARU (JP)
IWASE TAKASHI (JP)
OCHIAI KUNIYASU (JP)
YAJIMA MASAKO (JP)
TERAHARA MASAKI (JP)
NAKAMURA YOSHITAKA (JP)
TOTSUKA MAMORU (JP)
YAMADA KIYOSHI (JP)
International Classes:
A61K35/74; A23C9/127; A23C9/152; A23L1/30; A23L33/10; A23L33/135; A61K35/745; A61P37/04; C12N1/20; C12N15/09
Foreign References:
| JP2002255853A | 2002-09-11 | |||
| JP2005089388A | 2005-04-07 | |||
| JPH0761934A | 1995-03-07 | |||
| JPH04342533A | 1992-11-30 | |||
| JPH02280059A | 1990-11-16 | |||
| JP2004262773A | 2004-09-24 |
Other References:
PARK J.H. ET AL.: "ENCAPSULATED BIFIDOBACTERIUM BIFIDUM POTENTIATES INTESTINAL IGA PRODUCTION", CELL IMMUNOL., vol. 219, no. 1, 2002, pages 22 - 27, XP003001287
KO E.J. ET AL.: "BIFIDOBACTERIUM BIFIDUM EXHIBITS A LIPOPOLYSACCHARIDE-LIKE MITOGENIC ACTIVITY FOR MURINE B LYMPHOCYTES", JOURNAL OF DAIRY SCIENCE, vol. 82, no. 9, 1999, pages 1869 - 1876, XP003001288
HOSONO A. ET AL.: "Men'ekikei tp Sogosayo suru Chonai Saikin (Probiotics)", ALLERGOLOGY, vol. 18, no. 6, 2004, pages 483 - 489, XP003001289
See also references of EP 1854467A4
KO E.J. ET AL.: "BIFIDOBACTERIUM BIFIDUM EXHIBITS A LIPOPOLYSACCHARIDE-LIKE MITOGENIC ACTIVITY FOR MURINE B LYMPHOCYTES", JOURNAL OF DAIRY SCIENCE, vol. 82, no. 9, 1999, pages 1869 - 1876, XP003001288
HOSONO A. ET AL.: "Men'ekikei tp Sogosayo suru Chonai Saikin (Probiotics)", ALLERGOLOGY, vol. 18, no. 6, 2004, pages 483 - 489, XP003001289
See also references of EP 1854467A4
Attorney, Agent or Firm:
Hiraki, Yusuke (3-20 Toranomon 4-chom, Minato-ku Tokyo, JP)
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