COMPOSITION FOR INTERNAL USE

WIPO Patent Application WO/2014/163150

A1

Provided is a composition for internal use, which contains methylthioadenosine and is reduced in bitterness. This composition for internal use contains methylthioadenosine or a salt thereof (component (A)) and S-adenosylmethionine or a salt thereof (component (B)). The mass ratio of the component (A) (in terms of methylthioadenosine) to the component (B) (in terms of S-adenosylmethionine) is 0.05-1,000, and the content of the component (A) is 0.1% by mass or more in terms of methylthioadenosine.

WO/2011/158904	THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES CONTAINING ADENOSINE N1-OXIDE AS ACTIVE INGREDIENT
JP2007291135	PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING DISCOMFORT
JPS60184018	ANTIPROTOZOAL AGENT

SEKO TOMOMI (JP)
MIDORIKAWA TATSUYUKI (JP)
MONOI NORIYUKI (JP)
NAKAMURA YOSHITAKA (JP)
GOKITA TOSHIO (JP)
KAMADA IKUKO (JP)

PCT/JP2014/059867

October 09, 2014

April 03, 2014

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LION CORP (JP)

A61K31/7076; A23L27/00; A61K47/26; A61P25/20; A23L1/30

JP2005514356A	2005-05-19
JPS56166117A	1981-12-21
JPS5076215A	1975-06-21

MAKOTO TADENUMA ET AL.: "Seishu no Jukusei ni yoru Komi no Henka ni Kansuru Kenkyu (the 4th report)", JOURNAL OF THE BREWING SOCIETY OF JAPAN, vol. 70, no. 8, 1975, pages 585 - 587
MAGGINI, C. ET AL.: "A Polygraph Evaluation of the Effects of S-Adenosyl-L-Methionine(SAMe) on All-Night Sleep", MONOGRAPHIEN AUS DEM GESAMTGEBIETE DER PSYCHIATRIE, vol. 18, 1978, pages 151 - 169
MAKOTO TADENUMA ET AL.: "Seishu no Jukusei ni yoru Komi no Henka ni Kansuru Kenkyu (the 3rd report", JOURNAL OF THE BREWING SOCIETY OF JAPAN, vol. 70, no. 8, 1975, pages 581 - 584

SAKAI, Hiroaki et al. (JP)
Hiroaki Sakai (JP)

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