Title:
COMPOSITION FOR PATTERN RECOGNITION BASED TARGETING AND ACTIVATING AN INNATE IMMUNE RESPONSE
Document Type and Number:
WIPO Patent Application WO/2024/049790
Kind Code:
A3
Abstract:
Embodiments of a composition provide a line of defense against SARS coronaviruses that complements vaccines. The composition may be taken orally, intravenously, nasally, or inhaled by a healthy person to prevent a SARS infection or by a sick person infected by a SARS coronavirus for treatment. The composition is configured for molecular pattern recognition based targeting of the SARS coronavirus spike (S) protein and activating an innate immune response. The composition includes a lectin component. The composition may also include an optional flavonoid component, an optional calcium component, or both.
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Inventors:
LAU KEVIN (US)
CHAN LAWRENCE (US)
CHAN LAWRENCE (US)
Application Number:
PCT/US2023/031346
Publication Date:
April 11, 2024
Filing Date:
August 29, 2023
Export Citation:
Assignee:
PHYTO42 (US)
International Classes:
C07K14/42; A61P13/12; A61K9/00; A61K36/8962; A61K38/16; C07C15/00
Domestic Patent References:
| WO2021222965A1 | 2021-11-11 |
Foreign References:
| US20070287826A1 | 2007-12-13 |
Other References:
KEYAERTS ET AL.: "Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle", ANTIVIRAL RESEARCH, vol. 75, no. 3, September 2007 (2007-09-01), pages 179 - 187, XP022114357, DOI: 10.1016/j.antiviral.2007.03.003
ANNA MARIA SARDANELLI: "SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome", MOLECULES, MDPI AG, CH, vol. 26, no. 5, CH , pages 1409, XP093159937, ISSN: 1420-3049, DOI: 10.3390/molecules26051409
ANNA MARIA SARDANELLI: "SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome", MOLECULES, MDPI AG, CH, vol. 26, no. 5, CH , pages 1409, XP093159937, ISSN: 1420-3049, DOI: 10.3390/molecules26051409
Attorney, Agent or Firm:
WANG, Tina et al. (US)
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